In order to promote academic exchange and cooperation, CQMU invited Professor Dieter A. Wolf from the Technical University of Munich, Germany, to give an academic report in room 316 of the Second Teaching building on October 6. The meeting was presided over by Tian Jie, Vice President of CQMU and permanent member of the CQMU Party Committee , and 50 representatives of teachers and students attended.
Professor Wolf made a report entitled "Mechanisms of protein homeostasis and energy metabolism in cancer". In the study of protein homeostasis, Professor Wolf's team proposed that the loss of function of the eukaryotic translation initiation factor eIF3 will affect the elongation speed of ribosomes, which will lead to defects in protein synthesis related to mitochondria and membrane functions. This research provides a new idea for the research and clinical drug development of some major diseases related to mitochondria (such as malignant tumors and Alzheimer's disease, etc.). In terms of cancer energy metabolism research, Prof. Wolf's team analyzed the molecular mechanism of the small molecule compound SMIP004-7 to effectively inhibit mitochondrial oxidative phosphorylation (OXPHOS), which provided a new strategy for the treatment of drug-resistant cancer cells.
After the report, the participating teachers and students actively interacted with Professor Wolf and discussed relevant issues. The content of this academic report is ample and cutting-edge, and the academic atmosphere is strong, which helps to stimulate the academic innovation inspiration of the participating teachers and students, and provides a new impetus for the promotion of scientific and technological innovation in CQMU.
