On 31 March 2025, reporters learned from the Second Affiliated Hospital of Chongqing Medical University that the team led by Professor ZHANG Keqin from the Urology and Nephrology Centre, in collaboration with the teams of Professor LIN Tao and Professor SONG Turun from the Department of Urology/Kidney Transplantation Centre of West China Hospital, successfully overcame the worldwide challenge of ABO-incompatible kidney transplantation for the first time.
This study was the first to use enzyme treatment technology to transform a type B kidney into a universal type O kidney, which was then successfully transplanted into a brain-dead patient. The results were published in the international journal Nature Communications.
The research team pointed out that the next steps will focus on further optimising this technology to enable the conversion of kidneys of all blood types into type O kidneys. They also plan to promote more extensive clinical trials to accelerate the clinical translation of this technology and related products.
(Translated by AI)
