PERSONAL INFORMATION
Name: Chundong Zhang
Gender: Male
Title: Professor
Position: Department of Biochemistry and
Molecular Biology
CONTACT INFORMATION
Email: zhangcd@cqmu.edu.cn
RESEARCH INTERESTS
Reviewer for the National Natural Science Foundation of China. Main research interests include screening and identification of tumor biomarkers using lung cancer cells as a model, as well as analysis of their molecular mechanisms in cytoplasm (microfilaments)-nuclear lamina assembly and remodeling, resistance, and cellular senescence. Has successfully led multiple national and provincial-level research projects, accumulating research funding of over one million RMB. Published over 30 SCI papers in internationally recognized academic journals, including those Nature Index journals and top journals in the field of biochemistry such as the Journal of Biological Chemistry.
PUBLICATIONS
1. Zhili Wei; Ru Wang; Xun Yin; lian Zhang; Yunlong Lei; Ying Zhang; Jiaqian Wu; Youquan Bu; Guoxiang Jin; Chundong Zhang*. PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in Non-Small Cell Lung Cancer cells, Genes & Diseases, 2022, 9:230-244.
2. Lian Zhang; Ying Zhang; Yunlong Lei; Zhili Wei; Yi Li; Yingxiong Wang; Youquan Bu*; Chundong Zhang*. Proline-rich 11 (PRR11) drives F-actin assembly by recruiting the actin-related protein 2/3 complex in human non-small cell lung carcinoma, J. Biol. Chem., 2020, 295(16): 5335-5349. （Nature index期刊）
3. Lian Zhang; Yunlong Lei; Ying Zhang; Yi Li; Youquan Bu; Fangzhou Song*; Chundong Zhang*. Silencing of PRR11 suppresses cell proliferation and induces autophagy in NSCLC cells , Genes & Diseases, 2018, 5(2):158-166.
4. Yitao Wang #; Ying Zhang #; Chundong Zhang#; Huali Weng #; Yi Li; Wei Cai; Mengyu Xie; Yinjiang Long; Qing Ai; Zhu Liu; Gang Du; Sen Wang; Yulong Niu; Fangzhou Song; Toshinori Ozaki; Youquan Bu *. The gene pair PRR11 and SKA2 shares a NF-Y-regulated bidirectional promoter and contributes to lung cancer development, Biochimica et Biophysica Acta-Gene Regulatory Mechanisms, 2015, 1849(9): 1133-1144.
5. Chundong Zhang; Ying Zhang; Yi Li; Huifang Zhu; Yitao Wang; Wei Cai; Jiang Zhu; Toshinori Ozaki; Youquan Bu*. PRR11 regulates late-S to G2/M phase progression and induces premature chromatin condensation (PCC), Biochem Biophys Res Commun, 201
