PERSONAL INFORMATION
Name: Xiaohui Zhan
Gender: Female
Title: Associate Professor
Position: Vice director for Department of Bioinformatics
CONTACT INFORMATION
Email: xhzhan@cqmu.edu.cn
Address: 1 Yixueyuan Road, Yuzhong District,
Chongqing 400016, P.R.China
EDUCATION EXPERIENCE
• University of Chinese Academy of Sciences, Ph.D. in Bioinformatics, July 2017.
• Southwest Jiaotong University, B.Sc. in Bioinformatics, July 2012.
WORKING EXPERIENCE
• Associate Professor, Department of Bioinformatics, Chongqing Medical University, 2020– Present
• Assistant Scientist, Department of Medicine, Indiana University, 2018 – 2020
RESEARCH INTERESTS
• Translational bioinformatics and integrative genomics for Cancers
• Algorithms for mining large and complex biomedical data
• Medical image analysis
PUBLICATIONS
1. Wei W, Ye B, Huang Z, Mu X, Qiao J, Zhao P, Jiang Y, Wu J, Zhan X. Prediction of Prognosis, Immunotherapy and Chemotherapy with an Immune-Related Risk Score Model for Endometrial Cancer. Cancers (Basel). 2023 Jul 19;15(14):3673.
2. Zhan X, Liu Y, Jannu AJ, Huang S, Ye B, Wei W, Pandya PH, Ye X, Pollok KE, Renbarger JL, Huang K, Zhang J. Identify potential driver genes for PAX-FOXO1 fusion-negative rhabdomyosarcoma through frequent gene co-expression network mining. Front Oncol. 2023 Jan 30;13:1080989.
3. Lu Z†, Zhan X†, Wu Y, Cheng J, Shao W, Ni D, Han Z, Zhang J, Feng Q, Huang K. BrcaSeg: A Deep Learning Approach for Tissue Quantification and Genomic Correlations of Histopathological Images. Genomics Proteomics Bioinformatics. 2021 Dec;19(6):1032-1042. doi: 10.1016/j.gpb.2020.06.026. Epub 2021 Jul 17.
4. Zhan X, Liu Y, Yu CY, Wang TF, Zhang J, Ni D, Huang K. A pan-kidney cancer study identifies subtype specific perturbations on pathways with potential drivers in renal cell carcinoma. BMC Med Genomics. 2020 Dec 28;13(Suppl 11):190.
5. Zhan X, Cheng J, Huang Z, Han Z, Helm B, Liu X, Zhang J, Wang TF, Ni D, Huang K. Correlation Analysis of Histopathology and Proteogenomics Data for Breast Cancer. Mol Cell Proteomics. 2019 Aug 9;18(8 suppl 1):S37-S51.
6. Zhan X, Dong C, Liu G, Li Y, Liu L. Panel of seven long noncoding RNA as a candidate prognostic biomarker for ovarian cancer. Onco Targets Ther. 2017 Jun 1;10:2805-2813.
7. Liu G†, Zhan X†, Dong C†, Liu L. Genomics alterations of metastatic and primary tissues across 15 cancer types. Sci Rep. 2017 Oct 16;7(1):13262.
8. Helm BR, Zhan X, Pandya PH, Murray ME, Pollok KE, Renbarger JL, Ferguson MJ, Han Z, Ni D, Zhang J, Huang K. Gene Co-Expression Networks Restructured Gene Fusion in Rhabdomyosarcoma Cancers. Genes (Basel). 2019 Aug 30;10(9):665.
9. Huang Z, Zhan X, Xiang S, Johnson TS, Helm B, Yu CY, Zhang J, Salama P, Rizkalla M, Han Z, Huang K. SALMON: Survival Analysis Learning With Multi-Omics Neural Networks on Breast Cancer. Front Genet. 2019 Mar 8;10:166.
10. Liu Y, Ye X, Zhan X, Yu CY, Zhang J, Huang K. TPQCI: A topology potential-based method to quantify functional influence of copy number variations. Methods. 2021 Apr 22:S1046-2023(21)00107-9.
11. Cheng J, Liu Y, Huang W, Hong W, Wang L, Zhan X, Han Z, Ni D, Huang K, Zhang J. Computational Image Analysis Identifies Histopathological Image Features Associated With Somatic Mutations and Patient Survival in Gastric Adenocarcinoma. Front Oncol. 2021 Mar 31;11:623382.
12. Huang Z, Johnson TS, Han Z, Helm B, Cao S, Zhang C, Salama P, Rizkalla M, Yu CY, Cheng J, Xiang S, Zhan X, Zhang J, Huang K. Deep learning-based cancer survival prognosis from RNA-seq data: approaches and evaluations. BMC Med Genomics. 2020 Apr 3;13(Suppl 5):41.
13. Yu CY, Xiang S, Huang Z, Johnson TS, Zhan X, Han Z, Abu Zaid M, Huang K. Gene Co-expression Network and Copy Number Variation Analyses Identify Transcription Factors Associated With Multiple Myeloma Progression. Front Genet. 2019 May 17;10:468.
14. Liu G, Dong C, Wang X, Hou G, Zheng Y, Xu H, Zhan X, Liu L. Regulatory activity based risk model identifies survival of stage II and III colorectal carcinoma. Oncotarget. 2017 Sep 28;8(58):98360-98370.
15. Zhang M, Wang J, Jiang J, Zhan X, Ling Y, Lu Z, Guo J, Gao X. Von Hippel-Lindau disease type 2 in a Chinese family with a VHL p.W88X truncation. Endocrine. 2015 Feb;48(1):83-8.
CONFERENCE
• International Conference on Intelligent Biology and Medicine 2023
• International Conference on Intelligent Biology and Medicine 2022
• 2022 2nd IEEE International Conference on Information Communication and Software Engineering
• International Conference on Intelligent Biology and Medicine 2020
