PERSONAL INFORMATION
Name: Tang Yi
Gender: Female
Title: Associate Professor
CONTACT INFORMATION
Email: tangyi@cqmu.edu.cn
EDUCATION EXPERIENCE
2005.9-2010.7 Clinical Medicine(Reproductive direction), Bachelor,Chongqing Medical University
2010.9-2015.7 Pathology and Pathophysiology, MD-PhD,Chongqing Medical University
WORKING EXPERIENCE
2015.9-2020.9 Lecture,Chongqing Medical University
2020.10 to now, Associate Professor, Chongqing Medical University
RESEARCH INTERESTS
The long-term focus has been on the post-translational modification of proteins through mono- and poly-ADP ribosylation (MARylation and PARylation), with a particular emphasis on elucidating the mechanisms in the context of colorectal cancer proliferation, exosomes, and autophagy, among other related areas. With the goal of addressing clinical issues, foundational research is conducted to explore the impact of ADP ribosylation modifications on the development and drug resistance of colorectal cancer. This research aims to provide an experimental foundation for precision therapies in colorectal cancer.
HONOUR & AWARDS
Based on digital virtual technology, the construction and application of a medical morphology experimental teaching platform (8/9), Chongqing Teaching Achievement Award, Third Prize.
2020, Chongqing achieved excellence in offline courses, Pathology (6/6).
2022, Chongqing university curriculum ideological and political demonstration project, Pathology (6/8).
2022, Demonstration cases of first-class undergraduate courses in Chongqing, Providing multidimensional and comprehensive support for the development of content-rich pathology education (5/5).
PUBLICATIONS
1. Song Gang-Lin,Xiao Ming, Wang Xiao-Ya, Deng Jun, Ling Jun-Da, Tian Ying-Guo, Li Min,Yin Jie, Zheng Ren-Ying, Tang Yi* ;MiR-130a-3p suppresses colorectal cancer growth by targeting Wnt Family Member 1 (WNT1),Biogengineered,2021,12(1),8407-8418.
2. Wang Jie-Qiong#,Tang Yi#,Li Qing-Shu,Xiao, Ming,Li Ming, Sheng Yong-Tao,Yang Yi,Wang Ya -Lan* ; PARG regulates the proliferation and differentiation of DCs and T cells via PARP/NF-kappa B in tumor metastases of colon carcinoma, Oncology Reports, 2019, 41(5): 2657-2666 .
3. Zha Jing-Jing, Tang Yi #, Wang Ya-Lan*, Role of mono-ADP-ribosylation histone modification (Review), Experimental and Therapeutic Medicine ,2021,21: 577.
4. Zhou Li#, Zhan Mu-Lu#,Tang Yi#,Xiao Ming,Li Ming,Li Qing-Shu,Yang Lian, Li Xian, Chen Wen-Wen, Wang Ya-Lan*; Effects of β-caryophyllene on arginine ADP-ribosyltransferase 1 mediated regulation of glycolysis in colorectal cancer under high-glucose conditions, Journal of Oncology,2018, 4(53):1613-1624.
5. Ling Feng#, Tang Yi#, Li Ming;,Li Qing-Shu, Li Xian,Yang Lian,Zhao Wei, Jin Cong-Cong,Ze ng Zhen,Liu Chang, Wu Cheng Fang,Chen Wen-Wen, Lin Xiao, Wang Ya-Lan*,Threadgill MichaelD;Mono-ADP-ribosylation of histone 3 at arginine-117 promotes proliferation through its interaction with P300, Oncotarget, 2017, 8(42): 72773-72787.
6. Tang Yi, Li Ming,Wang Ya-Lan, Threadgill MichaelD,Xiao Ming,Mou Chun-Feng,Song Guang-Lin,Kuang Jing, Yang Xi, Yang Lian, Gao Xing-Jie, Wang Ya-Ping, Meng Yun-peng. ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma,2015,5(2):498-513.
7. Tangy Yi, Wang Ya-Lan*, Yang Lian, Xu Jian-Xia, Xiong Wei,Xiao Ming,Li Ming。Inhibition of arginine ADP-ribosyltransferase 1 reduces the expression of poly (ADP-ribose) polymerase-1 in colon carcinoma. International Journal of Molecular Medicine,2013,32:130-136.