PERSONAL INFORMATION
Name: Jianhua Ran , PhD
Gender: Female
Title: Professor
Position: Director of Department of Anatomy
CONTACT INFORMATION
Email: ranjianhua@cqmu.edu.cn
Address: 1st Yixueyuan Road, Yuzhong District, Chongqing 400016, P.R.China
Phone: +86-68485000
EDUCATION EXPERIENCE
1993.09 - 1998.06 |
Chongqing Medical University |
BA |
medicine |
2000.09 - 2005.06 |
Chongqing Medical University |
PhD |
Neurology |
WORKING EXPERIENCE
1998.07 - 2003.09 |
Chongqing Medical University |
Assistant Professor |
2003.09 - 2007.09 |
Chongqing Medical University |
Lecturer |
2007.09 - 2011.09 |
Chongqing Medical University |
Associate Professor |
2011.09 - 2013.09 |
Chongqing Medical University |
Associate Professor, Deputy director |
2013.09 - 2022.09 |
Chongqing Medical University |
Professor, Deputy director |
2022.09 - |
Chongqing Medical University |
Professor, Director |
RESEARCH INTERESTS
Neuroscience, Urea cycle unbalance in neurodegenerative diseases, psychiatric disorders and aging
HONOUR & AWARDS
2023.09 |
prominent teacher |
Chongqing Medical University |
2023.09 |
Qiande Teaching Master |
Chongqing Medical University |
2022.11 |
Chongqing Talent Teacher |
Organization Department of Chongqing Municipal Party Committee |
PUBLICATIONS
1. Boyue Huang, Zhizhen Huang, Hongkai Wang, Guoqi Zhu, Hui Liao, Zhiwen Wang, Baoxue Yang, Jianhua Ran. High urea induces anxiety disorders associated with chronic kidney disease by promoting abnormal proliferation of OPC in amygdala. European Journal of Pharmacology. 2023 Aug 26;957:175905.doi: 10.1016/j.ejphar.2023.175905.
2. Mengna Wu, Boyue Huang, Ling Hu, Tao Zhang, Binyu Zhang, Xi Zhao, Ruijin Lu , Wei Xiong, Shengyao Zhang, Jing Li, Dilong Chen, Baoxue Yang, Guoli Li, Jianhua Ran. Ganoderma lucidum polysaccharides ameliorates D-galactose-induced aging salivary secretion disorders by upregulating the rhythm and aquaporins. Exp Gerontol. 2023;112147.doi: 10.1016/j.exger.2023.112147.
3. Xiaoyan Wang, Juanjuan Zhang, Jiaqi Zhu, Zhenwei Yuan Hui Xu, Jianhua Ran. Monitoring isoniazid metabolism in vivo using a near-infrared fluorescent probe. Anal Methods. 2022 May 30.doi: 10.1039/d2ay00185c.
4. Dezhi Yuan, TianKuan, HuLing, Hongkai Wang, Liping Feng, Qiuye Zhao, Jinfang Li, Jianhua Ran. Serum metabolomics of end-stagerenal disease patients with depression: potential biomarkers for diagnosis. Renal failure. 2021, VOL. 43, NO. 1, 1479–1491.
5. Boyue Huang, Hongkai Wang, Dandan Zhong, Jia Meng, Min Li, Baoxue Yang, Jianhua Ran. Expression of Urea Transporter B in Normal and Injured Brain. Frontiers in Neuroanatomy, 2021;15:591726.doi: 10.3389/fnana.2021.591726.
6. Tao Zhang, Ling Hu, Jia-Feng Tang, Hang Xu, Kuan Tian, Meng-Na Wu, Shi-Ying Huang, Yu-Mei Du, Peng Zhou, Rui-Jin Lu, Shuang He, Jia-Mei Xu, Jian-Jun Si, Jing Li, Di-Long Chen, Jianhua Ran. Metformin Inhibits the Urea Cycle and Reduces Putrescine Generation in Colorectal Cancer Cell Lines. Molecules. 2021 Apr 1;26(7):1990.doi: 10.3390/molecules26071990.
7. Wang Hongkai, Huang Boyue, Wang Weiling, Li Jinfang, Chen Yi, Flynn Trevor, Zhao Meng, Zhou Zhiming, Lin Xiaojing, Zhang Yinan, Xu Mengmeng, Li Keqiong, Tian Kuan, Yuan Dezhi, Zhou Peng, Hu Ling, Zhong Dandan, Zhu Shuai, Li Jing, Chen Dilong, Wang Kejian, Liang Jianhui, He Qihua, Sun Jianbin, Shi Jie, Yan Li, Sands Jeff M, Xie Zhengwei, Lian Xuemei, Xu Duan, Ran Jianhua*, Yang Baoxue*. High urea induces depression and LTP impairment through mTOR signalling suppression caused by carbamylation. EBioMedicine. 2019:478-490.