PERSONAL INFORMATION
Name: Juan Huang
Gender: Female
Title: Professor
CONTACT INFORMATION
Email: huangjuan@cqmu.edu.cn
Address: Department of Anatomy & Institute of Neuroscience, Basic Medical College, Chongqing Medical University, Chongqing 400016, China
Phone: +86-15923291163
EDUCATION EXPERIENCE
1998.09-2003.06, Bachelor of Clinical Medicine
2003.09-2006.06, Master of Human Anatomy and Histoembryology
2011.09-2014.06, Doctor of Tissue Engineering and Cell Engineering
WORKING EXPERIENCE
2021.11 till now, Chongqing Medical University, Basic Medical College, Professor 2015.09-2021.10, Chongqing Medical University, Basic Medical College, Associate Professor
2008.09-2021.08, Chongqing Medical University, Basic Medical College, Lecturer
2006.07-2008.08, Chongqing Medical University, Basic Medical College, Assistant
RESEARCH INTERESTS
The pathogenesis and treatment of cerebrovascular diseases
PUBLICATIONS
1.Yang Z, Huang J(co-first author), Liao Y, Gan S, Zhu S, Xu S, Shu Y, Lu W. ER Stress is Involved in Mast Cells Degranulation via IRE1α/miR-125/Lyn Pathway in an Experimental Intracerebral Hemorrhage Mouse Model. Neurochem Res. 2022; 47(6):1598-1609.
2. Shu Y, Huang J(co-first author), Gao M, Gan S, Zhu S, Xu S, Yang Z, Liao Y, Lu W. Small Interfering RNA targeting DMP1 protects mice against blood-brain barrier disruption and brain injury after intracerebral hemorrhage. Journal of Stroke and Cerebrovascular Diseases. 2021;9;30(6):105760.
3. Gao M, Lu W, Shu Y, Yang Z, Sun S, Xu J, Gan S, Zhu S, Qiu G, Zhuo F, Xu S, Wang Y, Chen J, Wu X, Huang J (corresponding author). Poldip2 mediates blood-brain barrier disruption and cerebral edema by inducing AQP4 polarity loss in mouse bacterial meningitis model. CNS Neuroscience & Therapeutics. 2020;26(12):1288-1302.
4. Huang J (first author), Lu W, Doycheva DM, Gamdzyk M, Hu X, Liu R, Zhang JH, Tang J. IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model. Journal of Neuroinflammation. 2020;17(1):152.
5. Huang J(first author), Liu W, Doycheva DM, Gamdzyk M, Lu W, Tang J, Zhang JH. Ghrelin attenuates oxidative stress and neuronal apoptosis via GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway in a rat model of neonatal HIE. Free Radic Biol Med. 2019 Sep;141:322-337. )
6. Lu WT, Sun SQ, Li Y, Xu SY, Gan SW, Xu J, Qiu GP, Zhuo F, Huang SQ, Jiang XL, Huang J(corresponding author). Curcumin Ameliorates Memory Deficits by Enhancing Lactate Content and MCT2 Expression in APP/PS1 Transgenic Mouse Model of Alzheimer's Disease. Anat Rec (Hoboken). 2019 Feb;302(2):332-338.
7. Huang J(first author), Lu WT, Sun SQ, Yang ZB, Huang SQ, Gan SW, Xu J, Qiu GP, Zhuo F, Zhu SJ, Jiang J, Jiang XL. Upregulation and lysosomal degradation of AQP4 in rat brains with bacterial meningitis. Neurosci Lett. 2014 Apr 30;566:156-61.
8. Huang J(first author), Sun SQ, Lu WT, Xu J, Gan SW, Chen Z, Qiu GP, Huang SQ, Zhuo F, Liu Q, Xu SY. The internalization and lysosomal degradation of brain AQP4 after ischemic injury. Brain Res. 2013 Nov 20;1539:61-72.