PERSONAL INFORMATION
Name: Zhiwei Dong
Title: Professor
CONTACT INFORMATION
Email: zwdong@aliyun.com
Address: Department of Cell Biology and Genetics，
Chongqing Medical University, Chongqing, China
EDUCATION EXPERIENCE
Postdoctoral Research Fellow, Postdoctoral Research Fellow, Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA
Doctor of Philosophy, Genetics, Shanghai Institutes for Biological Sciences,
Chinese Academy of Sciences, Shanghai, China (2015)
Bachelor of Science, Biology, Yangzhou University, Yangzhou, China (2008)
RESEARCH INTERESTS
Research in the Dong lab focuses on the developmental biology and novel treatment strategies of childhood cancer, especially neuroblastoma. The primary aims of his lab is to discover novel genes affecting neuroblastoma development, as well as the roles of innate immune cells during metastasis of neuroblastoma.
PUBLICATIONS
1. Dong ZW, Gonzalo L, Alex GT, Xiaonan H, Gina R, Cheng Z, Erin DN, John M, Shizhen Z. Deficient GAS7 Expression Accelerates Neuroblastoma Metastasis in the Context of MYCN Overexpression. Cancer Research. 2021. (IF: 9.727)
2. Yu S-H, Zhu K-Y, Zhang F, Wang J, Yuan H, Chen Y, Jin Y, Dong M, Wang L, Jia X-E, Gao L, Dong ZW, Ren C-G, Chen L-T, Huang Q-H, Deng M, et al. The histone demethylase Jmjd3 regulates zebrafish myeloid development by promoting spi1 expression. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 2018. (IF: 4.6)
3. Zhang X, Dong ZW, Zhang C, Ung CY, He S, Tao T, Oliveira AM, Meves A, Ji B, Look AT, Li H, Neel BG, Zhu S. Critical Role for GAB2 in Neuroblastoma Pathogenesis through the Promotion of SHP2/MYCN Cooperation. Cell reports. 2017. (IF: 7.8)
4. Zhu S, Zhang X, Weichert-Leahey N, Dong ZW, Zhang C, Lopez G, Tao T, He S, Wood AC, Oldridge D, Ung CY, van Ree JH, Khan A, Salazar BM, Lummertz da Rocha E, Zimmerman MW, et al. LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis. Cancer cell. 2017. (IF: 23.9, co-second author)
5. Jia X-E, Ma K, Xu T, Gao L, Wu S, Fu C, Zhang W, Wang Z, Liu K, Dong M, Jing C, Ren C, Dong ZW, Chen Y, Jin Y, Huang Q, et al. Mutation of kri1l causes definitive hematopoiesis failure via PERK-dependent excessive autophagy induction. Cell research. 2015. (IF: 17.8)
6. Dong ZW, Ren C-G, Xia Y, Su D, Du T-T, Fan H-B, Yuan H, Wang L, Dong M, Li W-C, Jin Y, Chen Y, Deng M, Liu T-X, Gu A-H, Zhou Y. Pten regulates homeostasis and inflammation-induced migration of myelocytes in zebrafish. Journal of Hematology & Oncology. 2014. (IF: 11.059, first author)
7. Du T-T, Xu P-F, Dong ZW, Fan H-B, Jin Y, Dong M, Chen Y, Pan W-J, Ren R-B, Liu T-X, Deng M, Huang Q-H. Setdb2 controls convergence and extension movements during zebrafish gastrulation by transcriptional regulation of dvr1. Developmental Biology. 2014. (IF: 2.9)
8. Liu Y-J, Fan H-B, Jin Y, Ren C-G, Jia X-E, Wang L, Chen Y, Dong M, Zhu K-Y, Dong ZW, Ye B-X, Zhong Z, Deng M, Liu TX, Ren R. Cannabinoid receptor 2 suppresses leukocyte inflammatory migration by modulating the JNK/c-Jun/Alox5 pathway. The Journal of biological chemistry. 2013. (IF: 4.1)
9. Ren C-G, Wang L, Jia X-E, Liu Y-J, Dong ZW, Jin Y, Chen Y, Deng M, Zhou Y, Zhou Y, Ren R-B, Pan W-J, Liu T-X. Activated N-Ras signaling regulates arterial-venous specification in zebrafish. Journal of Hematology & Oncology. 2013. (IF: 11.059)
10. Fu C-T, Zhu K-Y, Mi J-Q, Liu Y-F, Murray ST, Fu Y-F, Ren C-G, Dong ZW, Dong M, Jin Y, Chen Y, Deng M, Zhang W, Chen B, Breslin P, Chen S-J, et al. An evolutionarily conserved PTEN-C/EBPalpha-CTNNA1 axis controls myeloid development and transformation. Blood. 2010. (IF: 16.6).
11. Li Q-F, Zhang G-Y, Dong Z-W, Yu H-X, Gu M-H, Sun SSM, Liu Q-Q. Characterization of expression of the OsPUL gene encoding a pullulanase-type debranching enzyme during seed development and germination in rice. Plant Physiology and Biochemistry. 2009. (IF: 3.4)
