Faculty & Research

College of Basic Medicine -- CHEN Quanmei

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PERSONAL INFORMATION

Name: Chen Quanmei

Gender: Female

 

CONTACT INFORMATION

Email: qmchen@cqmu.edu.cn

Address: Basic Medical College, Chongqing  Medical University

No.1, Yixueyuan Road, Yuzhong District, Chongqing,

P.R. China(Post code 400016)

Phone: +86-15123829730

 

EDUCATION EXPERIENCE

2009.9 –2015.9  Ph.D. studies in the State Key Laboratory of Silkworm Genome Biology, Southwest University

2005.9 –2009.6  B.S. major in Biotechnology in Southwest University, Chongqing, China.   

 

WORKING EXPERIENCE

2015-present  Department of Biochemistry and Molecular BiologyCollege of Basic Medicine at Chongqing Medical University.

 

RESEARCH INTERESTS

1.Tumor biology, cancer metabolismmetabolic reprogramming

2. Molecular mechanism and clinical significance of tumor related genes in cancer 

3. Cellular Biochemistry , Gene expression

 

HONOUR & AWARDS

1. National scholarship of the people’s republic of China  (9/2012 - 1/2013)

2. First class scholarship for outstanding graduate student , Southwest University (9/2012 - 6/2013)

 

PUBLICATIONS

1) Xinyan Wan , Junqi Xiang , Hui Fan , Ying Jiang, Yiting Lu, Chundong Zhang, Ying Zhang, Quanmei Chen*, Yunlong Lei*, Ciclopirox Olamine Induces Proliferation Inhibition and Protective Autophagy in Hepatocellular Carcinoma, Pharmaceuticals,2023,16,113. 

2) 2. Xing Xia, Chuntao Tao, Kailong Du, Peixin Meng, Lanyue Hu, Dong Cheng, Xianjun Liu, Youquan Bu Xiaoyan Fan*, Quanmei Chen*, SKA2-mediated transcriptional downregulation of the key enzyme of CoQ10 biosynthesis PDSS2 in lung cancer cells,Journal of Cancer,2023,14:322-335.

3) Lanyue Hu (#), Quanmei Chen(#), Yitao Wang, Na Zhang, Peixin Meng, Tong Liu, Youquan Bu (*),Sp1 mediates the constitutive expression and repression of PDSS2 gene in lung cancer cells[J]. Genes, 2019

4) Yun Li(#), Quanmei Chen(#),Chunxue Zhang, Chanjuan Yang, Youquan Bu, Yunmei Zhang (*). MicroRNA-454 enhances proliferation and migration in non-small cell lung cancer cells[J]. International Journal of Clinical and Experimental Medicine, 2019;12(6):6932-6945 

5) Quanmei Chen(#), Yun Li(#), Chunxue Zhang, Yitao Wang, Lian Zhang ,Fangzhou Song ,Youquan Bu (*). MicroRNA-301a promotes growth and migration by repressing TGFBR2 in non-small cell lung cancer[J]. International Journal of Clinical and Experimental Pathology,2017;10(2):957-971

6) Quanmei Chen(#), Xinyu Liu(#), Ping Zhao, Yanhui Sun, XinjieZhao, Ying Xiong, Guowang Xu(*), Qingyou Xia(*). GC/MS-basedmetabolomic studies reveal key roles of glycine in regulating silk synthesis insilkworm, Bombyx mori[J]. Insect Biochemistry and Molecular Biology,2015,57:41-50 

7) Quanmei Chen(#), Zhengang Ma, Xin Wang, Zhiqing Li, Yan Zhang, Sanyuan Ma, Ping Zhao(*), Qingyou Xia. Comparative proteomic analysis of silkworm fat body after knocking out fibroin heavy chain gene: a novel insight into cross-talk between tissues[J]. Functional & integrative genomics, 2015, 15(5):611-637

8) Quanmei Chen(#), Daojun Cheng, Shiping Liu, Zhengang Ma, Xiang Tan, Ping Zhao(*). Genome-wideidentification and expression profiling of the fattyacid desaturase gene family in the silkworm, Bombyx mori[J]. Genetics and Molecular Research, 2014, 13(2):3747-3760 

9) Quanmei Chen(#), Zhengang Ma, Xiaohuan Wang, Yanhui Sun, Xin Wang, Yunxiang Dai, Ping Zhao(*). Sequence Analysis and Prokaryotic Expression of a Sensory Neuron Membrane Protein Gene SNMP1 form Silkworm. Bombyx mori[J]. Science of Sericulture (Chinese). 2013, 39(2):231-239

10) Quanmei Chen(#), Daojun Cheng, Zhengang Ma, Xiaoming Hu, Xingfu Zha, Ping Zhao(*). Cloning of full-length cDNA and promoter sequences of fatty acid desaturase gene desat4 from silkworms, Bombyx mori and B. mandarina, and its prokaryotic expression [J]. Acta Entomologica Sinica (Chinese). 2012, 55(6):885-894

11) Quanmei Chen(#), Xiang Tan, Qiang Yang, Xiaoming Hu, Zhengang Ma, Ping Zhao(*). Identification and Expression Patterns of Atlastin Genes in Silkworm, Bombyx mori[J]. Science of Sericulture (Chinese). 2011, 37(2):206-214

12) Jing Zhou(#), Hao Liu(#), Lian Zhang(#),  Xin Liu, Chundong Zhang, Yitao Wang, Qing He, Ying Zhang, Yi, Quanmei Chen, Lu Zhang, Kui Wang, Youquan Bu, Yunlong Lei(*).DJ-1 promotes colorectal cancer progression through activating PLAGL2/Wnt/BMP4 axis J]. Cell Death and Disease, 2018 (9):865

13) Xin Wang(#), Yi Li, Qingsong Liu, Quanmei Chen, Qingyou Xia, Ping Zhao(*) . In vivo effects of metal ions on conformation and mechanical performance of silkworm silks[J]. Biochimica et Biophysica Acta (BBA) - General Subjects, 2017, 1861(3):567~576

14) Yi Li(#), Xin Wang, Quanmei Chen, Yong Hou, Qingyou Xia, Ping Zhao(*).Metabolomics analysis of the larval head of the silkworm, Bombyx mori[J]. International Journal of Molecular Sciences, 2016, 17(9):1460

15) Xin Tang(#), Huawei Liu, Quanmei Chen, Xin Wang, Ying Xiong, Ping Zhao(*).Genome-Wide identification, characterization and expression analysis of the solute carrier 6 gene family in silkworm (Bombyx mori) [J]. International Journal of Molecular Sciences, 2016,17(10):1675 

16) Yi Li(#), Xin Wang, Yong Hou, Xiaoying Zhou, Quanmei Chen, Chao Guo, Qingyou Xia, Yan Zhang, Ping Zhao(*). Integrative proteomics and metabolomics analysis of insect larva brain: novel insights intothe molecular mechanism of insect wandering behavior[J]. Journal Proteome Research, 2016, 15(1):193-204

17) Xin Wang(#), Yi Li, Kang Xie, Qiying Yi, Quanmei Chen, Xiaohuan Wang, Hong Shen, Qingyou Xia, Ping Zhao(*). Ca2+ and endoplasmic reticulum Ca2+-ATPaseregulate the formation of silk fiberswith favorable mechanical properties[J]. Journal of Insect Physiology,2015,73:53-59