PERSONAL INFORMATION
Name: Chen Di
Gender: Female
Title: Professor
CONTACT INFORMATION
Email: chendi@cqmu.edu.cn
Address: #1 Yixueyuan Road, Yu Zhong District, Chongqing, 400016, China
EDUCATION EXPERIENCE
1992.9 - 1997.7, Bachelor, Clinical Medicine, Chongqing Medical University
1999.9 - 2002.7, Master, Physiology, Chongqing Medical University
2007.9 - 2011.7, PhD, Tissue and Cell Engineering, Chongqing Medical University
WORKING EXPERIENCE
1997.7 - 2002.8, Assistant, Department of Physiology, College of Basic Medical Sciences, Chongqing Medical University
2002.9 - 2007.8, Lecturer, Department of Physiology, College of Basic Medical Sciences, Chongqing Medical University
2007.9 - 2018.8, Associate professor, Department of Physiology, College of Basic Medical Sciences, Chongqing Medical University
2013.7 - 2014.8, Visiting scholar, Department of Physiology and Pharmacology, Loma Linda University
2018.9 to present, Professor, Department of Physiology, College of Basic Medical Sciences, Chongqing Medical University
RESEARCH INTERESTS
Professor Chen has been engaged in research on the cerebral vascular diseases and psychoses. Her most recent work mainly focuses on pathogenesis and drug treatment of hypoxic-ischemic brain damage and autism. Prof. Chen has undertaken 1 project of National Natural Science Foundations of China, 1 project of Chongqing Science and Technology Commission. She has participated in more than 10 National Natural Science Foundations of China, Chongqing Science and Technology Commission and Chongqing Education Commission.
PUBLICATIONS
1. Di Chen, Jiping Tang, Nikan H Khatibi, Mei Zhu, Yingbo Li, Chengyuan Wang, Rong Jiang, Liu Tu, Shali Wang*. Treatment with Z-ligustilide, a component of Angelica sinensis, reduces brain injury after a subarachnoid hemorrhage in rats. J Pharmacol Exp Ther. 2011;337(3):663-72.
2. Qin Hu, Xiping Liang, Di Chen, Yujie Chen, Desislava Doycheva, Junjia Tang, Jiping Tang, John H Zhang*. Delayed hyperbaric oxygen therapy promotes neurogenesis through reactive oxygen species/hypoxia-inducible factor-1α/β-catenin pathway in middle cerebral artery occlusion rats. Stroke. 2014 Jun;45(6):1807-14.
3. Xiping Liang, Qin Hu, Bo Li, Devin McBride, Hetao Bian, Pierre Spagnoli, Di Chen, Jiping Tang, John H Zhang. Follistatin-like 1 attenuates apoptosis via disco-interacting protein 2 homolog A/Akt pathway after middle cerebral artery occlusion in rats. Stroke. 2014;45(10):3048-54.
4. Di Chen, Brandon J Dixon, Desislava M Doycheva, Bo Li, Yang Zhang, Qin Hu, Yue He, Zongduo Guo, Derek Nowrangi, Jerry Flores, Valery Filippov, John H Zhang, Jiping Tang*. IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic–ischemic brain injury in rats. J Neuroinflammation. 2018 15(1):32.
5. Junying Lan, Yuling Hu, Xiaoqing Wang, Wenxia Zheng, Ailing Liao, Shali Wang, Yingbo Li, Yan Wang, Feng Yang, Di Chen*. Abnormal spatiotemporal expression pattern of progranulin and neurodevelopment impairment in VPA-induced ASD rat model. Neuropharmacology. 2021;196:108689.
6. Lili Wang, Jianhui Chen, Yuling Hu, Ailing Liao, Wenxia Zheng, Xiaoqing Wang, Junying Lan, Jingjing Shen, Shali Wang, Feng Yang, Yan Wang, Yingbo Li, Di Chen*. Progranulin improves neural development via the PI3K/Akt/GSK-3β pathway in the cerebellum of a VPA-induced rat model of ASD. Transl Psychiatry. 2022 ;12(1):114.
