PERSONAL INFORMATION
Name: DAVID PAUL MOLLOY
Gender: male
Title: Professor
CONTACT INFORMATION
Email: 190495@cqmu.edu.cn
Address: Chongqing Medical University, 1 Medical College Road, Yuzhong District, Chongqing, China
Phone: +86-15310382117
EDUCATION EXPERIENCE
October 1984 - June 1987: BSc (Hons) Applied Biology, Portsmouth Institute of Technology, UK
October 1987 - March 1991: PhD in Biochemistry and Biophysics, National Institute for Medical Research, UK
WORKING EXPERIENCE
July 1990 - July 1992 Postdoctoral Fellow, Department of Biochemistry, Baylor College of Medicine, USA
July 1992 - March 2000 Associate Professor, Senior Research Fellow, Master Tutor, University of Birmingham, UK
March 2000 - March 2002 Senior Lecturer, Associate Professor, doctoral Supervisor, University of Bedford, UK
March 2002 - March 2009 Head of Research Office and Professor of Biochemistry, PhD Supervisor, University of West London, UK
June 2009 - July 2016 Principal, International College, University of Portsmouth, UK
August 2016 - July 2019 Professor of Biochemistry and Molecular Biology, Hunan University of Arts and Sciences, China Foreign expert
From July 2019 to the present, Professor of Biochemistry and Molecular Biology at the School of Basic Medicine of Chongqing Medical University, Foreign expert and doctoral supervisor in China has been recognised as a high-level, sophisticated and foreign talent in Chongqing in 2023
RESEARCH INTERESTS
Research is focused on three main areas, including:
1. Structure and function of adenovirus early Region 1A protein (Ad E1A) and its role in cell transformation and tumorigenesis.
2. Studies on the role of adenovirus early 1B 55K protein and its function in RNA editing, prevention of apoptosis and cell transformation
HONOUR & AWARDS
2019: Excellence Award for Foreign Teacher Training and Exchange by Beijing Oriental-British International Education Institute
PUBLICATIONS
1) Liu D, Li ZA, Li Y, Molloy DP, Huang C. (2023). The DYW domain of RARE1 plays an indispensable role in regulating accD-C794 RNA editing in Arabidopsis thaliana. Plant Sci. 2023 334:111751.
2) Huang C, Liu D, Li ZA, Molloy DP, Luo ZF, Su Y, Li HO, Liu Q, Wang RZ, Xiao LT. (2023). The PPR protein RARE1-mediated editing of chloroplast accD transcripts is required for fatty acid biosynthesis and heat tolerance in Arabidopsis. Plant Commun. 4(1):100461.
3) Li Y, Peng Q, Jiang N, Molloy DP, Zeng C, Wu Q. (2022) Computed tomography imaging features of malignant 'triton' tumor to facilitate its clinical diagnosis: report of two cases. BMC Med Imaging. 22(1):125. doi: 10.1186/s12880-022-00848-9.
4) Yu X, Chen J, Tang H, Tu Q, Li Y, Yuan X, Zhang X, Cao J, Molloy DP, Yin Y, Chen D, Song Z, Xu P. (2022). Identifying Prokineticin2 as a Novel Immunomodulatory Factor in Diagnosis and Treatment of Sepsis. Crit Care Med. 50(4):674-684. doi: 10.1097/CCM.0000000000005335.
5) Guo P, Zhang Y, Zhang L, Xu H, Zhang H, Wang Z, Jiang Y-L, Molloy D, Zhao P, Xia Q (2021). Structural basis for juvenile hormone biosynthesis by the juvenile hormone acid methyltransferase. J. Biol Chem. doi.org/10.1016/j.jbc.2021.101234
6) Liquiritigenin Promotes Osteogenic Differentiation And Prevents Bone Loss Via Inducing Auto-lysosomal Degradation And Inhibiting Apoptosis. Qiu Y, Zhao Y, Long Z, Song A, Huang P, Wang K, Xu L, Molloy DP, He G. (2021) Genes and Disease. doi.org/10.1016/j.gendis.2021.06.008
7) Molloy DP, Grand RJA. (2020) Structural Determinants within the Adenovirus Early Region 1A Protein Spacer Region Necessary for Tumorigenesis J Virol. 94, DOI: 10.1128/JVI.01268-20.
8) Mutation of chloroplast CHLM contributes to down-regulation of multiple stress response genes in Arabidopsis. Huang C, Molloy DP, Cao Z-L, Xiao L-T. (2020) Plant Growth Regulation. DOI:10.1007/s10725-020-00600-9
9) Huang, C, Li Z-R, Yu Q-B, Cui Y-L, Molloy DP, Yang Z-N. (2019) MORF2 tightly associates with MORF9 to regulate chloroplast RNA editing in Arabidopsis. Plant Sci. 278: 64-69.
