PERSONAL INFORMATION
Name: Lingyu Li
Birth Date: Nov. 12, 1986
Tel.: 13883084317
E-mail: 102815@cqmu.edu.cn
Address: No. 1, Medical School Road, Yuzhong District, Chongqing
EDUCATION EXPERIENCE
2006.09-2011.06 Weifang Medical University Clinical Medicine (Bachelor)
2011.09-2016.06 Chongqing Medical University Pathology and Pathophysiology (Doctor)
WORKING EXPERIENCE
2016.09-2019.10 Chongqing Medical University Lecture
2019.11-now Chongqing Medical University Associate professor
HONOURS & AWARDS
1. The second prize of “Chongqing Medical University Teachers' Teaching Innovation Competition in 2022 ”.
2. The first prize of “the Fifth Young Pathologist Picture recognition Competition of Chongqing Medical Association”.
3. Excellent annual assessment of public institutions in Chongqing in 2021.
4. Excellent annual assessment of public institutions in Chongqing in2020.
RESEARCH INTERESTS
1. Mechanism of Endogenous small molecule Protective protein on Cerebral Ischemia-reperfusion injury.
2. Focus on the difference of internal protective mechanism between neurons and glial cells during cerebral ischemia-reperfusion injury, and to find differential genes to interfere with neurons and reduce neuronal injury.
FOUNDATIONS
1. National Natural Science Foundation of China (No. 81801183), " The Effects and Mechanism of Prdx6-iPLA2 activity in promoting Cerebral Ischemia-reperfusion injury by activating NLRP3 inflammatory complex", 2019. 01-2021:.12, Participate.
2. National Natural Science Foundation of China (No.81801506), "The Mechanism of Sortilin regulating PGRN on neuronal endoplasmic reticulum stress in neonatal hypoxic-ischemic encephalopathy", 2019.01-2021.12, Participate.
3. National Natural Science Foundation of China (No. 81701165), "The roles and Mechanism of Sestrin2 activating Nrf2/HO-1 pathway in promoting angiogenesis after cerebral ischemia", 2018.01-2020.12, Host.
4. National Natural Science Foundation of China (No. 81771261), "The Mechanism of SCO-spondin protein Regulatory Network involved in Stroke", 2018.01-2021.12, Participate.
PUBLICATIONS
1. Platonin protects against cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasomes via BNIP3/LC3 signaling mediated autophagy[J]. Brain Res Bull. 2022 Mar;180:12-23. （Co-corresponding author）
2. The Valuable Role of ARMC1 in Invasive Breast Cancer as a Novel Biomarker[J]. BioMed Research International. 2022; doi: 10.1155/2022/1740295.
3. Sestrin2 promotes angiogenesis to alleviate brain injury by activating Nrf2 through regulating the interaction between p62 and Keap1 following photothrombotic stroke in rats[J]. Brain Research. 1745(2020)146948. （Co-corresponding author）
4. Sestrin2 overexpression attenuates focal cerebral ischemia injury in rat by increasing Nrf2/HO-1 pathway-mediated angiogenesis[J]. Neuroscience. 410 (2019) 140-149. （Co-corresponding author）
5. Sestrin2 Silencing Exacerbates Cerebral Ischemia/Reperfusion Injury by Decreasing Mitochondrial Biogenesis through the AMPK/PGC-1α Pathway in Rats[J]. Sci Rep. 2016; 6:30272. doi: 10.1038/srep30272.（First author）
6. Targeting thioredoxin-1 with siRNA exacerbates oxidative stress injury after cerebral ischemia/reperfusion in rats[J]. Neuroscience. 2015 284: 815-823.（First author）
7. Targeting thioredoxin-1 with siRNA exacerbates oxidative stress injury after cerebral ischemia/reperfusion in rats[J]. Neuroscience. 2015 284: 815-823.（First author）
