Faculty & Research

College of Basic Medicine -- ZHANG Lidan

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PERSONAL INFORMATION

Name: Zhang Lidan

Gender: Female

Title: Associate professor


CONTACT INFORMATION

Email: zlidan@cqmu.edu.cn

Phone: +86- 15320345027


EDUCATION EXPERIENCE

2010.4-2014.3 Bachelor of Engineering B.S. Takusyoku University Japan  2015.4-2017.3 Master of Pharmacy (MSc degree) Osaka University Japan

2017.4-2020.3 PhD in Pharmacy Osaka University Japan


WORKING EXPERIENCE

2020.4-2022.3 Research Associate Osaka University Japan

2022.3- Associate professor Basic Medical Sciences, Chongqing Medical University


RESEARCH INTERESTS

1.   Skeletal muscle ageing

2.   Skeletal muscle stem cell

3.   Skeletal muscle degenerative diseases

4.   Exercise and Skeletal Muscle Stem Cells


PUBLICATIONS

1. Kubota, M., Zhang,L, and So-Ichiro Fukada (2023). Flow Cytometer Analyses, Isolation, and Staining of Murine Muscle Satellite Cells. Methods in Molecular Biology, 3– 11.https://doi.org/10.1007/978-1-0716-3036-5_1.

2. Xiang, C., Hu, N*., Hu, N*., Zhang, L*., Zou, R., Li, A., Liu, F., Huang, K., Wen, J., Wang, S., et al. (2023). A Bioinspired Smart Adhesion Actuator with Fast‐Driving and SelfSensing Capability. Advanced Materials Technologies. https://doi.org/10.1002/admt.202201715.

3. Kaneshige, A., Kaji, T., Zhang,L., Saito, H., Nakamura, A., Kurosawa, T., Ikemoto-Uezumi, M., Tsujikawa, K., Seno, S., Hori, M., et al. (2021). Relayed Signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell responses to increased mechanical load. Cell stem cell. https://doi.org/10.2139/ssrn.3815989.

4. Zhang,L., Kubota, M., Nakamura, A., Kaji, T., Seno, S., Uezumi, A., Andersen, D.C., Jensen, C.H., and Fukada, S. (2020). Dlk1 regulates quiescence in calcitonin receptor-mutant muscle stem cells. Stem Cells. 39, 306–317. https://doi.org/10.1002/stem.3312.

5. Zhang,L., Noguchi, Y.-T., Nakayama, H., Kaji, T., Tsujikawa, K., Ikemoto-Uezumi, M., Uezumi, A., Okada, Y., Doi, T., Watanabe, S., et al. (2019). The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells. Cell Reports.29, 2154-2163.e5.https://doi.org/10.1016/j.celrep.2019.10.057.

6. Zhang,L.J.M.Sci., Akiyoshi Uezumi, Kaji, T., Kazutake Tsujikawa, Ditte Caroline Andersen, Charlotte Harken Jensen, and So-ichiro Fukada (2019). 

Expression and Functional Analyses of Dlkin Muscle Stem Cells and Mesenchymal Progenitors during Muscle Regeneration. Int J Mol Sci. 20, 3269–3269. https://doi.org/10.3390/ijms20133269.

7. Fukuda, S., Kaneshige, A., Kaji, T., Noguchi, Y., Takemoto, Y., Zhang,L., Tsujikawa, K., Kokubo, H., Uezumi, A., Maehara, K., et al. (2019). Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle. eLife.https://doi.org/10.7554/elife.48284.

8. Ikemoto-Uezumi, M., Uezumi, A., Zhang,L, Zhou, H., Hashimoto, N., Okamura, K., Matsui, Y., Tsukazaki, K., Hosoyama, T., Nakatani, M., et al. (2019). Reduced expression of calcitonin receptor is closely associated with age-related loss of the muscle stem cell pool. JCSM Rapid Communications.2, 1– 13. https://doi.org/10.1002/j.2617-1619.2019.tb00012.x.

9. Noguchi, Y., Nakamura, M., Hino, N., Nogami, J., Tsuji, S., Sato, T., Zhang,L., Kazutake Tsujikawa, Tanaka, T., Izawa, K., et al. (2019). Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites. Development.https://doi.org/10.1242/dev.163618.

10. Takemoto, Y., Inaba, S., Zhang,L., Kazutake Tsujikawa, Akiyoshi Uezumi, and Satoshi Fukada (2018). Implication of basal lamina dependency in survival of Nrf2‐null muscle stem cells via an antioxidative‐independent mechanism. J Cell Physiol..234, 1689– 1698.https://doi.org/10.1002/jcp.27040.

11. Militello, G., Gellert, P., Weirick, T., John, D.M., Hindi, S.M., Döring, C., Zhang, L., Nakamura, M., Kumar, A., So-ichiro Fukada, et al. (2018). A novel long non-coding RNA Myolinc regulates myogenesis through TDP-43 and Filip1. JMol Cell Biol. 10, 102– 117.https://doi.org/10.1093/jmcb/mjy025.

12. Takei, D., Nishi, M., So-ichiro Fukada, Doi, M., Okamura, H., Akiyoshi Uezumi, Zhang,L., Yoshida, M., Mikiya Miyazato, Ichimura, A., et al. (2017). Gm7325 is MyoD-dependently expressed in activated muscle satellite cells. BiomedRes. 38215–219.https://doi.org/10.2220/biomedres.38.215.

13. Takemoto, Y., Inaba, S., Zhang,L., Baba, K., Hagihara, K., and Fukada, S. (2017). An herbal medicine, Go-sha-jinki-gan (GJG), increases muscle weight in severe muscle dystrophy model mice. Clinical Nutrition Experimental 16, 13–23.

https://doi.org/10.1016/j.yclnex.2017.08.003.

14. Yamaguchi, M., Murakami, S., Yoneda, T., Nakamura, M., Zhang,L., Akiyoshi Uezumi, Fukuda, S., Hiroki Kokubo, Kazutake Tsujikawa, and So-ichiro Fukada (2015). Evidence of Notch-Hesr-Nrf2 Axis in Muscle Stem Cells, but Absence of Nrf2 Has No Effect on Their Quiescent and Undifferentiated State. PLoS One. 10e0138517–e0138517.https://doi.org/10.1371/journal.pone.0138517.