PERSONAL INFORMATION
Name: Xuemei Zhang
Gender: Female
Title: Professor
Position: None
CONTACT INFORMATION
Email: zhangxuemei@cqmu.edu.cn
Address: Chongqing Med Univ, Minist Educ, Key Lab Diagnost Med Designated, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China.
Phone: +86- 13594116299
EDUCATION EXPERIENCE
2000-2003 Chongqing Medical University (CQMU) Laboratory Ph.D
Medicine
1997-2000 West China Center of Medical Sciences, Sichuan University M.S.
Biochemicals and molecular biology
1991-1995 West China Center of Medical Sciences, Sichuan University B.S
Pharmaceutical chemistry
WORKING EXPERIENCE
Years Rank Institution Department/College
1995-2000 Teaching assistant Chongqing Med. University Dept. of Bas. Med.
2000-2004 Lecturer Chongqing Med. University Dept. of Bas. Med
2004-2009 Associate Professor Chongqing Med. University Dept. of Lab. Med.
2009- Professor Chongqing Med. University Dept. of Lab. Med.
RESEARCH INTEREST WORKING EXPERIENCES
Study on the Role of Immune Regulation in the Prevention and Treatment of infectious diseases and Immune Disorders
HONOUR & AWARDS
2011 Chongqing Municipal Natural Science Prize two. Rank second
PUBLICATIONS（Representative Publications）
1. Zhu T, Zhang H, Li S, Wu K, Yin Y, Zhang X. Detoxified pneumolysin derivative ΔA146Ply inhibits autophagy and induces apoptosis in acute myeloid leukemia cells by activating mTOR signaling. Exp Mol Med. 2022 May;54(5):601-612. doi: 10.1038/s12276-022-00771-7.
2. Zhang J, Ye W, Wu K, Xiao S, Zheng Y, Shu Z, Yin Y, Zhang X*. Inactivation of Transcriptional Regulator FabT Influences Colony Phase Variation of Streptococcus pneumoniae. mBio. 2021 Aug 31;12(4):e0130421. doi: 10.1128/mBio.01304-21.
3. Gou X, Yuan J, Wang H, Wang X, Xiao J, Chen J, Liu S, Yin Y, Zhang X*. IL-6 During Influenza-Streptococcus pneumoniae Co-Infected Pneumonia-A Protector. Front Immunol. 2020 Jan 21;10:3102. doi: 10.3389/fimmu.2019.03102.
4. Wang X, Yuan J, Wang H, Gan N, Zhang Q, Liu B, Wang J, Shu Z, Rao L, Gou X, Zhang H, Yin Y, Zhang X*. Progranulin Decreases Susceptibility to Streptococcus pneumoniae in Influenza and Protects against Lethal Coinfection. J Immunol. 2019 Oct 15;203(8): 2171-2182. doi: 10.4049/jimmunol.1900248.
5. Wu J, Wu K, Xu W, Yuan T, Wang X, Zhang J, Min Y, Yin Y, Zhang X*. Engineering detoxified pneumococcal pneumolysin derivative ΔA146PLY for self-biomineralization of calcium phosphate: Assessment of their protective efficacy in murine infection models. Biomaterials. 2018 Feb;155:152-164. doi: 10.1016/j.biomaterials.2017.11.018.
