Faculty & Research

College of Pharmacy -- PENG Yongbo

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PERSONAL INFORMATION

Name: Yongbo Peng

Gender: Male

Title: Hongkong Scholar

Position: Professor


CONTACT INFORMATION

Email: pengyongbo2021@cqmu.edu.cn; pengyongbo2000@126.com 

Address: College of Pharmacy, Chongqing Medical University, No. 1, Yixueyuan Road, Chongqing 400016, PR China

Phone: +86-023-6848 5161


EDUCATION EXPERIENCE

2008.09-2011.07 Ph.D., State Key Laboratory for Natural Medicines, China Pharmaceutical University, Nanjing, China.

2005.09-2008.07 M.S., College of Pharmacy Chongqing Medical University, Chongqing, China.

2000.09-2004.07 B.Sc., Science of Chinese Pharmacology, Hunan University of TCM, Changsha, China.


WORKING EXPERIENCE

2021.05-now Professor, College of Pharmacy Chongqing Medical University, Chongqing, China.

2020.10-2021.04 Professor, College of Clinical Pharmacy, Guangdong Pharmaceutical University, Guangzhou, China.

2018.11-2022.09 Senior Researcher, College of Biology, State Key Laboratory for Chemo/Bio-Sensing and Chemometrics, Hunan University, Changsha, China.

2018.01-2018.10 Postdoctoral Fellow, HKU Li Ka Shing Faculty of Medicine, Hongkong, China.

2014.07-2017.05 Postdoctoral Fellow, Associate Professor, State Key Laboratory for Chemo/Bio-Sensing and Chemometrics, Hunan University, Changsha, China.

2011.08-2014.06 Associate Professor, College of Pharmacy, Jinan University, Guangzhou, China.

2004.05-2005.08 Research Assistant, Hunan institute of traditional Chinese medicine (TCM), Changsha, China.


RESEARCH INTERESTS

(1) Natural products and aptamer drug conjugated system and its molecular pharmacology;

(2) Translational research based on protein self-assembly micro-nano technology, such as skin repair and aging, AD, PD, stroke, depression, inflammatory bowel disease, etc.


HONOUR & AWARDS

(1) Hongkong Scholar (Hongkong University, 1/1; 2017)

(2) The Distinguished Paper Award of the Chinese Pharmaceutical Society (1/10; 2013)

(3) The Second Prize of Science and Technology Progress of Guangdong Province (4/8; 2023)

(4) The Third Prize of Chongqing Banan "Help you set sail" start-up firms’ competition (1/10; 2022)


PUBLICATIONS

As the first/co-first author or corresponding/co-corresponding author published SCI papers > 30, including Mol Cancer, Angew Chem Int Ed Engl., J Am Chem Soc., ACS Nano, Nanoscale, Oncogene, Biomaterials, National Science Review. and Signal Transduct Target Ther., with 10 representing papers listed below.

1. Peng Y#, Zhao Z*#, Liu T#, Li X, Hu X, Wei X, Zhang X, Tan W*. Smart human serum albumin-As2O3 nanodrug with self-amplified folate receptor-targeting ability for chronic myeloid leukemia treatment. Angew Chem Int Ed Engl. 2017; 56(36): 10845-9.

2. Xu K#, Huang P#, Wu Y, Liu T, Zhao L, Peng Y*, Qu S*. Engineered selenium/human serum albumin nanoparticles efficiently targeted the treatment of Parkinson’s disease via oral administration. ACS Nano. 2023 (Revision)

3. Liu Q#, Peng Y#, Zhou P, Qi L, Zhang M, Gao N*, Liu E*, Li P*. 6-Shogaol induces apoptosis in human leukemia cells through a process involving caspase-mediated cleavage of eIF2α. Mol Cancer. 2013;12(1):135.

4. He J#, Peng T#, Peng Y#, Ai L#, Deng Z, Wang X*, Tan W*. Molecularly Engineer Triptolide with Aptamers for High Specificity and Cytotoxicity for Triple-Negative Breast Cancer. J Am Chem Soc. 2020; 142(6): 2699-703.

5. Wang D#, Peng R#, Peng Y#, Deng Z, Xu F, Su Y, Wang P, Li L, Wang X*, Ke Y*, Tan W*. Hierarchical Fabrication of DNA Wireframe Nanoarchitectures for Efficient Cancer Imaging and Targeted Therapy. ACS Nano 2020; 14(12): 17365-17375.

6. Xiang W#, Peng Y#, Zeng H#, Yu C#, Zhang Q, Liu B, Liu J, Hu X, Wei W, Deng M, Wang N, Liu X, Xie J, Hou W, Tang J, Long Z, Wang L, Liu J*. Targeting treatment of bladder cancer using PTK7 aptamer-gemcitabine conjugate. Biomater Res. 2022; 26(1):74.

7. Liu B#, Wang J#, Peng Y#, Zeng H, Zhang Q, Deng M, Xiang W, Liu J, Hu X, Liu X, Xie J, Hou W, Tang J, Long Z, Wang L, Liu J*. CD71/CD44 dual-aptamer-gemcitabine conjugate for tumor co-targeting treatment of bladder cancer. CHEM ENG J. 2023 Mar 24. doi: 10.1016/j.cej.2023.142597.

8. Deng L, Gao Y, Zhong G*, Song Q, Peng Y*, Zhu Z*. Effects of konjac glucomannan on physicochemical and rheological properties of whole egg liquid and in vitro fermentation of egg curd. Int J Biol Macromol. 2023 Jul 4; 246:125695.

9. Deng L#, Zeng H#, Hu X#, Xiao M, He D, Zhang Y, Jin Y, Hu Y, Zhu Y, Gong L, Wang Z, Xiang L, Zhu R, Zhang Y, Cheng Y, Chen X, Zhang S, Peng Y*, Cao K*. Se@Albumin nanoparticles ameliorate intestinal mucositis caused by cisplantin through the gut microbiota targeted regulation. Nanoscale. 2021; 13(25):11250-11261.

10. Peng Q, Wan D, Zhou R, Luo H, Wang J, Ren L, Zeng Y, Yu C, Zhang S, Huang X*, Peng Y*. The biological function of metazoan-specific subunit nuclear factor related to kappaB binding protein of INO80 complex. Int J Biol Macromol. 2022; 203:176-183.