PERSONAL INFORMATION
Name: LIU Yan
Gender: Female
Title: Associate Professor
Position: Associate Professor
CONTACT INFORMATION
Email: y.liu@cqmu.edu.cn
EDUCATION EXPERIENCE
1998.09-2003.05, Chongqing Medical University, Bachelor of Medicine
2007.09-2009.05, Aston University, Master of Drug Delivery
2013.09-2016.05, Chongqing Medical University, Ph.D.
WORKING EXPERIENCE
2009.05-2020.12, Lecturer, Department of Clinical Pharmacy, College of Pharmacy, Chongqing Medical University
2020.12 till now, Associate Professor, Department of Clinical Pharmacy, College of Pharmacy, Chongqing Medical University
RESEARCH INTERESTS
Have many years of work experience in new drug research and development, especially in the field of pharmacokinetics and pharmacodynamics research in clinical research of new drugs.
Participated in the compilation of the "Guidelines for the Development and Evaluation of Biomimetic Drugs (Trial)", "Guidelines for the Clinical Physiological Research of Antibody Drugs", and "Guidelines for the Study of Human Bioequivalence of Chemical Drug Genetics with Pharmacokinetic Parameters as Endpoint Evaluation Indicators".
HONOUR & AWARDS
Youth May 4th Red Bannerman of Chongqing Medical University in 2012.
PUBLICATIONS
1. Shilong Yang, Fu Gao*, Yan Liu et al, Safety and immunogenicity of a recombinant tandem-repeat dimeric RBD-based protein subunit vaccine (ZF2001) against COVID-19 in adults: two ran-domised, double-blind, placebo-controlled, phase 1 and 2 trials [J]. Lancet Infect Dis，2021(8):1107-1119，(IF:56.3)
2. Wei Shi, Ping Zhang, Feng Zou, Jiaqi Zhou, Ziyu Yin, Zilong Cai, Hesham Ghaleb, Yuxuan Jiang, Wenlong Huang, Yan Liu*, Qian qian Qiu, Hai Qian，Exploration of novel phthalazinone derivati-ves as potential efflux transporter inhibitors for reversing multidrug resistance and improving the oral absorption of paclitaxel [J]. European Journal of Medicinal Chemistry,2022.114231. (IF:7.08)
3. Yudong Zhang , Yue Jiang, Ya Wang, Ling Wang, Weijie Han , Xiaoyi Cheng, Xue Deng ,Chunmeng Qin and Yan Liu*，An UPLC-MS/MS Method for Routine Quantification of Insulin Degludec in plasma [J].Current Pharmaceutical Analysis，2020. 16. 792-799.(IF:0.92)
4. Li J, Liu Y*, Li H, et al. pH-Sensitive micelles with mitochondria-targeted and aggregation-induced emission characterization:synthesis, cytotoxicity and biological applications[J]. Biomaterials Science,2018,6(11):2998-3008.(IF:5.83)
5. Yan L*, Chen L, Jiaqi Z, et al. Novel Benzodiazepines Derivatives as analgesic Modulating for Transient receptor potential vanilloid 1 [J]. Bioorganic & Medicinal Chemistry,2018,26(15):4567-4573.(IF:2.88)
6. Chen Liao, Yan Liu*, Chunxia Liu, Jiaqi Zhou, Huilan Li, Nasi Wang, Jieming Li,Taiyu Liu, Hesham Ghaleb, Wenlong Huang, Hai Qian.Phenylquinoline transient receptor potential vanilloid 1 antagonists for the treatment of pain:Discovery of 1-(2-phenylq-uinoline-4-carbonyl)-N-(4 (trifluoromethyl)phenyl) pyrrolidine-3-carboxamide[J]. Bioorganic & Medi-cinal Chemistry,2018,26(4): 845-854.(IF:2.88)
7. Ma, H., Chen, G., Wang, T., Li, Q. and Liu, Y*. Design, Synthesis, and Biological Ev-aluation of a Novel Water-soluble Prodrug of Docetaxel with Amino Acid as a Linker[J]. Chem Biol Drug Des, 2016,88(3): 363-369. (IF:3.37)
8. Liu Y*, Xu X, Xie J, et al. Design, Synthesis,and Biological Evaluation of Novel CNS 7056 Derivatives as Sedatives in Rats and Rabbits[J]. Chemical Biology & Drug Design, 2016, 88(1):38-42.(IF:2.4)
9. Yan Liu*, Yan-Wu Li, Ya-Lan Tang, Xin Liu, Jun-Hao Jiang, Qing-Gen Li and JianYong Yuan. Vitamin D: Preventive and Therapeutic Potential in Parkinson’s disease[J]. Current Drug Metabolism, 2013, 14(9):989-993.(IF:3.49)
10. Liu Y*,Yang M S,Yuan J Y. Immunosuppressant utilization andcardiovascular complic-ations among Chinese patients after kidney transplantation : a systematic review and ana-lysis[J]. InternationalUrology & Nephrology,2013,45(3):885-892. (IF:1.293)
11. Jiang JH, Liu Y*, Wang YJ, et al. Clinical pharmacy education in China[J]. Am J Pharm Educ. 2011;75(3):57c. (IF:1.3)
