Faculty & Research

College of Pharmacy -- HE Baicheng

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PERSONAL INFORMATION

Name: Baicheng He

Gender: Male

Title: Professor

Position: Deputy Director of Chongqing key laboratory of biochemistry and molecular pharmacology

 

CONTACT INFORMATION

Email: bche@cqmu.edu.cn

Address: No. 1, Yixueyuan Road, Yuzhong District Chongqing 400016, Chongqing

Phone: +86-13310218650

 

EDUCATION EXPERIENCE

1993-1996:  Bachelor in Pharmacy, Chongqing Medical University, Chongqing, China.

2000-2003:  MS in Pharmacology, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China.

2008-2010:  MD in Molecular Pharmacology, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China

 

WORKING EXPERIENCE

1996.09-2000.06: Internship/resident, Yuxi Hospital, Chongqing, China.

2000.07-2003.06: MS graduate student in molecular pharmacology, School of Basic Medical Sciences, Chongqing Medical University, Chongqing, China.

2003.07-present: Department of Pharmacology, Chongqing Medical University, Chongqing, China.

2008.03-2010.03: Postdoctoral training in the Molecular Oncology Laboratory of University of Chicago.

 

RESEARCH INTERESTS

1. To investigate mechanisms behind the anti-tumor and chemopreventive activity of compounds from Chinese herbs.

2. To investigate the effect of bone morphogenetic proteins on adult stem cell osteogenic differentiation, the mechanism glucocorticoids induced osteoporosis (GIOP), and the strategy to reverse this toxicity or prevent from GIOP.

3. To investigate the effect of nuclear receptor agonists on chemotherapy in human osteosarcoma as differentiation inducing agents.


HONOUR & AWARDS

1993-1994: Student in Academic Excellence Award by Chongqing Medical University.

1994-1995:  Student in Academic Excellence Award by Chongqing Medical University.

1996: Excellent Graduate Award by Chongqing Medical University.

2016: Chongqingy young and middle-aged backbone teachers in universities

 

PUBLICATIONS

Recent publication:

1. Zhu JH, Liao YP, Li FS, Hu Y, Li Q, Ma Y, Wang H, Zhou Y, He BC, Su YX. Wnt11 promotes BMP9-induced osteogenic differentiation through BMPs/Smads and p38 MAPK in mesenchymal stem cells. J Cell Biochem, 2018, 119(11): 9462-9473.

2. Liao YP, Du WM, Hu Y, Li FS, Ma Y, Wang H, Zhu JH, Zhou Y, Li Q, Su YX, He BC. CREB/Wnt10b mediates the effect of COX-2 on promoting BMP9-induced osteogenic differentiation via reducing adipogenic differentiation in mesenchymal stem cells. J Cell Biochem, 2019, 120(6):9572-9587.

3. He F, Wang H, Ren WY, Ma Y, Liao YP, Zhu JH, Cui J, Deng ZL, Su YX, Gan H, He BC. BMP9/COX-2 axial mediates high phosphate-induced calcification in vascular smooth muscle cells via Wnt/β-catenin pathway. J Cell Biochem. 2018 Mar;119(3):2851-2863.

4. Liu RX, Ren WY, Ma Y, Liao YP, Wang H, Zhu JH, Jiang HT, Wu K, He BC, Sun WJ. BMP7 mediates the anticancer effect of honokiol by upregulating p53 in HCT116 cells. Int J Oncol. 2017, 51(3): 907-917.

5. Zeng YH, Zhou LY, Chen QZ, Li Y, Shao Y, Ren WY, Liao YP, Wang H, Zhu JH, Huang M, He F, Wang J, Wu K, He BC. Resveratrol inactivates PI3K/Akt signaling through upregulating BMP7 in human colon cancer cells. Oncol Rep. 2017, 38(1):456-464.

6. Chen QZ, Li Y, Shao Y, Zeng YH, Ren WY, Liu RX, Zhou LY, Hu XL, Huang M, He F, Sun WJ, Wu K, He BC. TGF-β1/PTEN/PI3K signaling plays a critical role in the anti-proliferation effect of tetrandrine in human colon cancer cells. Int J Oncol. 2017, 50(3): 1011-1021

7. Shao Y, Chen QZ, Zeng YH, Li Y, Ren WY, Zhou LY, Liu RX, Wu K, Yang JQ, Deng ZL, Yu Y, Sun WJ, He BC. All-trans retinoic acid shifts rosiglitazone-induced adipogenic differentiation to osteogenic differentiation in mouse embryonic fibroblasts. Int J Mol Med. 2016, 38(6):1693-1702.

8. Zhang RX, Li Y, Tian DD, Liu Y, Nian W, Zou X, Chen QZ, Zhou LY, Deng ZL, He BC. Ursolic acid inhibits proliferation and induces apoptosis by inactivating Wnt/β-catenin signaling in human osteosarcoma cells. Int J Oncol. 2016, 49: 49: 1973-1982.

9. Ren CM, Li Y, Chen QZ, Zeng YH, Shao Y, Wu QX, Yuan SX, Yang JQ, Yu Y, Wu K, He BC, Sun WJ. Oridonin inhibits the proliferation of human colon cancer cells by upregulating BMP7 to activate p38 MAPK. Oncol Rep. 2016 May;35(5):2691-8.

10. Wu QX, Yuan SX, Ren CM, Yu Y, Sun WJ, He BC, Wu K. Oridonin upregulates PTEN through activating p38 MAPK and inhibits proliferation in human colon cancer cells.  Oncol Rep. 2016 Jun;35(6):3341-8.

11. Yuan SX, Wang DX, Wu QX, Ren CM, Li Y, Chen QZ, Zeng YH, Shao Y, Yang JQ, Bai Y,          Zhang P, Yu Y, Wu K, Sun WJ, He BC. BMP9/p38 MAPK is essential for the antiproliferative      effect of resveratrol on human colon cancer. Oncol Rep. 2016 Feb;35(2):939-47.

12. Wu K, Zhou M, Wu QX, Yuan SX, Wang DX, Jin JL, Huang J, Yang JQ, Sun WJ, Wan LH, He BC. The role of IGFBP-5 in mediating the anti-proliferation effect of tetrandrine in human colon cancer cells. Int J Oncol. 2015,46(3):1205-13.

13. Huang J, Chen ZH, Ren CM, Wang DX, Yuan SX, Wu QX, Chen QZ, Zeng YH, Shao Y, Li Y, Wu K, Yu Y, Sun WJ, He BC. Antiproliferation effect of evodiamine in human colon cancer cells is associated with IGF-1/HIF-1α downregulation. Oncol Rep. 2015 Dec;34(6):3203-11

14. Huang J, Yuan SX, Wang DX, Wu QX, Wang X, Pi CJ, Zou X, Chen L, Ying LJ, Wu K, Yang JQ, Sun WJ, Deng ZL, He BC. The role of COX-2 in mediating the effect of PTEN on BMP9 induced osteogenic differentiation in mouse embryonic fibroblasts. Biomaterials. 2014 35(36):9649-59 (IF:8.557)

15. Yang Liu, Ying-Zi Liu, Ran-Xi Zhang,Zi-Jun Meng, Hun Huang, Ke Wu, Jin-Yong Luo, Guo-Wei Zuo, Liang Chen, Liang-Jun Yin, Zhong-Liang Deng, Bai-Cheng He. Oridonin inhibits the proliferation of human osteosarcoma cells by suppressing Wnt/β-catenin signaling. International Journal of Oncology,  2014; 45(2): 795-803 (IF: 2.773)

16. Ying-Zi Liu, Ke Wu, Jun Huang, Yang Liu, Xin Wang, Zi-Jun Meng, Shuang-Xue Yuan, Dong-Xu Wang, Jin-Yong Luo, Guo-Wei Zuo, Liang-Jun Yin, Liang Chen, Zhong-Liang Deng, Jun-Qin Yang, Wen-Juan Sun, Bai-Cheng He. The PTEN/PI3K/Akt and Wnt/β-catenin signaling pathways are involved in the inhibitory effect of resveratrol on human colon cancer cell proliferation. International Journal of Oncology, 2014; 45(1): 104-112 (IF: 2.773)

17. Yang Liu, Yin-Zi Liu, Ran-Xi Zhang, Xing Wang, Zi-Jun Meng, Mao Nie, Zheng-Jian Yan, Jun Huang, Long-Yang Zhou, Qiu-Jun Yang, Ke Wu, Jie-Li Jin, Jin-Yong Luo, Liang Chen, Liang-Jun Yin, Bai-Cheng He, Zhong-Liang Deng. All-trans retinoic acid modulates bone morphogenic protein 9-induced osteogenesis and adipogenesis of preadipocytes through BMP/Smad and Wnt/β-catenin signaling pathways. The International Journal of Biochemistry & Cell Biology. 2013; 47C:47-56. (IF: 4.152)

18. Wang Y, Wu NN, Mu YQ, Zhang RX, Hu M, Li RD, Chen L, He BC, Deng ZL. The effect of adenovirus-mediated siRNA targeting BMPR-II on UHMWPE-induced osteoclast formation. Biomaterials. 2013, 34(1):150-9.

19. Jin-Hua Wang, Ying-Zi Liu, Liang-Jun Yin, Liang Chen, Jun Huang, Yang Liu, Ran-Xi Zhang, Long-Yang Zhou, Qiu-Jun Yang, Jin-Yong Luo, Guo-wei Zuo, Zhong-Liang Deng, Bai-Cheng He. BMP9 and COX-2 Form an Important Regulatory Loop in BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells. Bone, 2013; 57(1): 311-321 (IF:4.461)

20. Qiujun Yang, Longyang Zhou, Yuqin Mu, Qixin Zhou, Jinyong Luo, Lang Cheng,      Zhongliang Deng, Tongchuan He, Rex C. Haydon and Baicheng He.  All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation. International Journal of Oncology, 2012; 41: 153-160

21. Ke Wu, Qiujun Yang, Yuqin Mu, Longyang Zhou, Yinzi Liu, Qixin Zhou and Baicheng He. Berberine inhibits the proliferation of colon cancer cellsby inactivating Wnt/β-catenin signaling International Journal of Oncology, 2012; 41: 292-298

22. Bai-Cheng He, Jian-Li Gao, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Ke Yang, Eric R. Wagner, Linyuan Wang, Ni Tang, Jinyong Luo, Xing Liu, Mi Li, Yang Bi, Jikun Shen, Gaurav Luther, Ning Hu, Qixin Zhou, Hue H. Luu, Rex C. Haydon, Yingming Zhao, and Tong-Chuan He. Tetrandrine Inhibits Wnt/β-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer.  Molecular Pharmacology, 2011; 79(2):211-219

23. Bai-Cheng He, Jian-Li Gao, Xiaoji Luo, Jinyong Luo, Jikun Shen, Linyuan Wang, Qixin Zhou, Yi-Tao Wang, Hue H. Luu, Rex C. Haydon, Chong-Zhi Wang, Wei Du, Chun-Su Yuan, Tong-Chuan He and Bing-Qiang Zhang. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/β-catenin signaling. International Journal of Oncology, 2011; 38: 437-445

24. Jinyong Luo, Min Tang, Jiayi Huang, Bai-Cheng He, Jian-Li Gao, Liang Chen, Guo-Wei Zuo, Wenli Zhang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Yang Bi, Xiaoji Luo, Wei Jiang, Yuxi Su, Jikun Shen, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Jian-Zhong Zhou, Ke Yang, Hue H. Luu, Xiaochuan Pan, Rex C. Haydon, Zhong-Liang Deng, and Tong-Chuan He. TGFb/BMP Type I Receptors ALK1 and ALK2 Are Essential for BMP9-Induced Osteogenic Signaling in Mesenchymal Stem Cells. Journal of Biological Chemistry, 2010; 285(38): 29588-29598 

25. Bai-Cheng He,  Liang Chen, Guo-Wei Zuo, Wenli Zhang, Yang Bi, Jiayi Huang, Yi Wang, Wei Jiang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Bo Liu,  Xia Lei, Jinyong Luo, Xiaoji Luo, Eric Wagner, Stephanie H. Kim, Connie J. He, Yawen Hu, Jikun Shen, Qixin Zhou, Farbod Rastegar, Zhong-Liang Deng, Hue H. Luu, Tong-Chuan He, and Rex C. Haydon.  Synergistic antitumor effect of the activated PPARγ and retinoid receptor on human osteosarcoma.  Clinical Cancer Research, 2010; 16(8) :2235-2245.

26. Wenli Zhang, Zhong-Liang Deng, Liang Chen, Guo-Wei Zuo, Qing Luo , Qiong Shi , Bing-Qiang Zhang, Eric R. Wagner , Farbod Rastegar, Stephanie H. Kim, Wei Jiang , Jikun Shen , Enyi Huang , Yanhong Gao , Jian-Li Gao, Jian-Zhong Zhou, Jinyong Luo, Jiayi Huang ,   Xiaoji Luo , Yang Bi, Yuxi Su, Ke Yang , Hao Liu, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, Bai-Cheng He. Retinoic Acids Potentiate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells.  PLoS ONE, 2010; 5(7) e11917

27. Liang Chen, Wei Jiang, Jiayi Huang,  Bai-Cheng He,  Guo-Wei Zuo, Wenli Zhang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Eric R. Wagner, Jinyong Luo, Min Tang, Christian Wietholt,  Xiaoji Luo, Yang Bi, Yuxi Su, Bo Liu, Stephanie H. Kim, Connie J. He, Yawen Hu, Jikun Shen, Farbod Rastegar, Enyi Huang, Yanhong Gao, Jian-Li Gao, Jian-Zhong Zhou, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Zhong-Liang Deng. Insulin-like Growth Factor 2 (IGF2) Potentiates BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells and Bone Formation.  Journal of Bone and Mineral Research, 2010; 25(11): 2447-2459

28. Zhang Y, Wu XH, Luo CL, Zhang JMHe BC, Chen G. Interleukin-12-anchored exosomes increase cytotoxicity of T lymphocytes by reversing the JAK/STAT pathway impaired by tumor-derived exosomes. Int J Mol Med. 2010; 25(5):695-700.

29. Eric Wagner, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Wenli Zhang, Qiong Shi, Qing Luo, Xiaoji Luo, Bo Liu, Jinyong Luo, Farbod Rastegar, Connie J. He, Yawen Hu, Barrett Boody, Hue H. Luu, Tong-Chuan He, Zhong-Liang Deng, and Rex C. Haydon. Therapeutic Implications of PPAR in Human Osteosarcoma.  PPAR Research,  2010; 2010:956427. Epub 2010 Feb 16.

30. Guo-Wei Zuo, Christopher D. Kohls, Bai-Cheng He, Liang Chen, Wenli Zhang, Qiong Shi, Bing-Qiang Zhang, Quan Kang, Jinyong Luo, Xiaoji Luo, Eric R. Wagner, Stephanie H. Kim, Farbod Restegar, Rex C. Haydon, Zhong-Liang Deng, Hue H. Luu, Tong-Chuan He, and Qing Luo. The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histology and Histopathology, 2010; 25: 795-806 

31. Farbod Rastegar, Deana Shenaq, Jiayi Huang, Wenli Zhang, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H Kim, Jian-Zhong Zhou, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R Reid, Hue H Luu, Rex C Haydon, Zhong-Liang Deng, Tong-Chuan He. Mesenchymal stem cells: Molecular characteristics and clinical applications. World J Stem Cells, 2010; 2(4): 67-80

32. Farbod Rastegar, Jian-Li Gao, Deana Shenaq, Qing Luo, Qiong Shi, Stephanie H. Kim, Wei Jiang, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jikun Shen, Ke Yang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Jinyong Luo, Xiaoji Luo, Yang Bi, Xing Liu, Mi  Li, Ning Hu, Linyuan Wang, Gaurav Luther, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He. Lysophosphatidic acid acyltransferase b (LPAATb) promotes tumor growth of human osteosarcoma.  PLoS One , 2010;  5(12):e14182

33. Eric R. Wagner, Gaohui Zhu, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Farbod Rastegar, Ke Yang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Yang Bi, Yuxi Su, Jinyong Luo, Xiaoji Luo, Jiayi Huang, Zhong-Liang Deng, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and  Tong-Chuan He. Therapeutic Potential of the Wnt Signaling Pathway in Bone Metabolic Disorders.   Current Molecular Pharmacology, 2011, 4(1):14-25.

34. Deana S. Shenaq, Farbod Rastegar, Djuro Petkovic, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Ke Yang, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R. Reid, Hue H. Luu, Rex C. Haydon and Tong-Chuan He.  Mesenchymal Progenitor Cells and Their Orthopedic Applications:  Forging a Path towards Clinical Trials.  Stem Cells International, 2010: 519028

35. Jiayi Huang, Yang Bi, Gao-Hui Zhu, Yun He, Yuxi Su, Bai-Cheng He, Yi Wang, Quan Kang, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Ailong Huang, Lan Zhou, Tao Feng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Ni Tang. Retinoic acid signaling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver International, 2009; 29(10): 1569-1581.

36. Gao-Hui Zhu, Jiayi Huang, Yang Bi, Yuxi Su, Yi Tang , Bai-Cheng He, Yun He, Jinyong Luo, Yi Wang, Liang Chen, Guo-Wei Zuo, Wei Jiang, Qing Luo, Jikun Shen, Bo Liu, Wen-Li Zhang, Qiong Shi, Bing-Qiang Zhang, Quan Kang, Jing Zhu, Jie Tian, Hue H. Luu, Rex C. Haydon, Yuan Chen, and Tong-Chuan He. Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation, 2009; 78: 195–204.

37. Yang Bi, Jiayi Huang, Yun He, Gao-Hui Zhu, Yuxi Su, Bai-Cheng He, Jinyong Luo, Yi Wang, Quan Kang, Qing Luo, Liang Chen, Guo-Wei Zuo, Wei Jiang, Bo Liu, Qiong Shi, Min Tang, Bing-Qiang Zhang, Yaguang Weng, Ailong Huang, Lan Zhou, Tao Feng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Ni Tang. Wnt Antagonist SFRP3 Inhibits the Differentiation of Mouse Hepatic Progenitor Cells. Journal of Cellular Biochemistry. 2009; 108(1):295-303

38. Yuxi Su, Xiaoji Luo, Bai-Cheng He, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Yang Bi, Jiayi Huang, Gao-Hui Zhu, Yun He, Quan Kang, Jinyong Luo, Jikun Shen, Jin Chen, Xianqing Jing, Rex C. Haydon, Tong-Chuan He, and Hue H. Luu. Establishment and characterization of a new highly metastatic human osteosarcoma cell line.  Clinical & Experimental Metastasis. 2009; 26:599–610.

39. Ni Tang, Wen-Xin Song, Jinyong Luo, Xiaoji Luo, Jin Chen, Katie A.Sharff, Yang Bi, Bai-Cheng He, Jia-Yi Huang, Gao-Hui Zhu, Yu-Xi Su, Wei Jiang, Min Tang, Yun He, Yi Wang, Liang Chen, Guo-Wei Zuo, Jikun Shen, Xiaochuan Pan, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He. BMP9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/β-catenin signaling. Journal of Cellular and Molecular Medicine. 2009; 13 (8B):2448-2464.

40. Katie A. Sharff, Wen-Xin Song, Xiaoji Luo, Ni Tang, Jinyong Luo, Jin Chen, Yang Bi, Bai-Cheng He, Jiayi Huang, Xinmin Li, Wei Jiang, Gao-Hui Zhu, Yuxi Su, Yun He, Jikun Shen, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Xiaochuan Pan, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He. Hey1 Basic Helix-Loop-Helix (bHLH) Protein Plays an Important Role in Mediating BMP9 Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells. Journal of Biological Chemistry. 2009; 284(1):649-659

41. Quan Kang, Wen-Xin Song, Qing Luo, Ni Tang, Jinyong Luo, Xiaoji Luo, Jin Chen, Yang Bi, Bai-Cheng He, Jong Kyung Park, Wei Jiang, Yi Tang, Jiayi Huang, Yuxi Su, Gao-Hui Zhu, Yun He, Hong Yin, Zhenming Hu, Yi Wang, Liang Chen, Guowei Zuo, Xiaochuan Pan, Jikun Shen, Tamara Vokes, Russell Reid, Rex C. Haydon, Hue H. Luu, and Tong-Chuan He. A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells.  Stem Cells and Development. 2009; 18(4): 545-559

42. Xiaoji Luo, Jin Chen, Wen-Xin Song, Ni Tang, Jinyong Luo, Zhong-Liang Deng, Katie A. Sharff, Gary He, Yang Bi, Bai-Cheng He, Erwin Bennett, Jiayi Huang, Quan Kang, Wei Jiang, Yuxi Su, Gao-Hui Zhu, Hong Yin, Yun He, Yi Wang, Jeffrey S. Souris, Liang Chen, Guo-Wei Zuo, Anthony G. Montag, Russell Reid, Rex C. Haydon, Hue H. Luu, and Tong-Chuan He. Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects.  Laboratory Investigation. 2008; 88(12):1264-1277.

43. Xiaoji Luo, Chong-Zhi Wang, Jin Chen, Wen-Xin Song, Jinyong Luo, Ni Tang, Bai-Cheng He, Quan Kang, Yitao Wang, Wei Du, Tong-Chuan He, and Chun-Su Yuan. Characterization of gene expression regulated by American ginseng and ginsenoside Rg3 in human colorectal cancer cells. International Journal of Oncology. 2008; 32: 975-983.

44. Yang Jun-Qing, Liu Bei-Zhong, He Bai-Cheng, Zhou Qi-Xin. Protective effects of meloxicam on aluminum overload-induced cerebral damage in mice. European Journal of Pharmacology. 2006; 547:52–58