PERSONAL INFORMATION
Name: Xia Yin-Yin
Gender: Female
Title: Professor
CONTACT INFORMATION
Email: 100118@cqmu.edu.cn
Address: School of Public Health
Chongqing Medical University, Chongqing 400016, China
EDUCATION EXPERIENCE
1. Sept. 2008--Jun.2011, Ph.D, Major: Clinical Laboratory Diagnostics, School of Public Health, Chongqing Medical University
2. Sept. 2009--Jun, 2010. Dr Cheng Yu Tung Fellowships. The University of Hong Kong Li Ka Shing Faculty of Medicine
3. Sept. 2007 -- Jan. 2008, a visiting scholar, studied and researched at Tongji Medical University，China.
4. Sept. 2002 -- June. 2005, M.Sc.Med., Major: Epidemiology and statistics, School of Public Health, Chongqing Medical University
5. Sept. 1997 -- June 2002, B.Sc.Med, Major: Preventive medicine, School of Public Health, Chongqing Medical University
WORKING EXPERIENCE
1. Nov.2021--present, Professor, School of Public Health, Chongqing Medical University
2. Oct.2017--Oct.2018,Visiting fellow, College of Life Sciences，University of Leicester
3. Sep.2013--Nov.2021,Associate professor, School of Public Health and Management，Chongqing Medical University
4. Oct.2011-- Oct.2012, Chinese Teacher, Mauritius. The 3th group of Mauritius volunteer program supported by Chongqing Municipal Committee of the Communist Youth League of China
5. Aug. 2007 -- Sep. 2013, Lecturer, School of Public Health, Chongqing Medical University
6. July. 2005 -- July. 2007, Teaching assistant, School of Public Health, Chongqing Medical University
RESEARCH INTERESTS
Mainly engaged in research on the effects of the environment on human health, including the effects of environmental pollutants on reproductive health, environmental epidemiology, birth cohort studies.
PUBLICATIONS
1. Yue Liu , Yang Yang, Yin-Yin Xia, Jamie V. de Seymour , De-Zhang Zhao,Yang-Mei Li,Hua Zhang , Ting-Li Han .An Evaluation of Different Digestion Methods for the Quantitation of Inorganic Elements in Human Hair Using ICP-MS. J Anal Methods Chem. 2022 Dec 1;2022:5742468.(IF=2.594)
2. Mei-Ling Zhao#, Feng-Jing Zhang#, Wen-Rong Jiang#, Yinyin Xia*, Chang Chen, Ting Zhang, Ting-Li Han, Xin-Yang Yu, Peter Mei, Hong-Mei Zhang,, Xin Jin,, Boris Novakovic, Pamela Leong, Murray Thompson, Richard Saffery, Richard D Cannon, Hua Zhang*, Ping Ji*．Investigating the impact of oral health on pregnancy and offspring outcomes: protocol for the Lifetime Impact of ORal heAlth (LIORA) cohort study. BMJ Open. 2022 Nov 29;12(11):e066204.(IF=3.006)
3. Jamie V de Seymour*, Kathryn L Beck, Cathryn A Conlon, Mary Beatrix Jones, John Colombo, Yin-Yin Xia*, Ting-Li Han, Hong-Bo Qi, Hua Zhang, Philip N Baker. An Investigation of the Relationship Between Dietary Patterns in Early Pregnancy and Maternal/Infant Health Outcomes in a Chinese Cohort. Frontiers in nutrition. 2022;9:775557. (IF=6.59)
4. Yue Liu#, Yin-Yin Xia#, Ting Zhang, Yang Yang, Richard D Cannon, Toby Mansell, Boris Novakovic, Richard Saffery, Ting-Li Han*, Hua Zhang*, Philip N Baker. Complex Interactions Between Circulating Fatty Acid Levels, Desaturase Activities, and the Risk of Gestational Diabetes Mellitus: A Prospective Cohort Study. Frontiers in nutrition. 2022;9:919357. (IF=6.59).
5. Xuyang Chen，Xue Zhao，Mary Beatrix Jones，Alexander Harper ，Jamie V. de Seymour ，Yang Yang，Yinyin Xia，Ting Zhang，Hongbo Qi，John Gulliver，Richard D. Cannon，Richard Saffery，Hua Zhang，Ting-Li Han，Philip N. Baker．The relationship between hair metabolites, air pollution exposure and gestational diabetes mellitus: A longitudinal study from pre-conception to third trimester. Front Endocrinol (Lausanne). 2022 Dec 2;13:1060309. (IF=6.055)
6. Xiao ling He，Xiao jing Hu，Bai yu Luo，Yin Yin Xia，Ting Zhang，Richard Safery， Jamie De Seymour5，Zhen Zou，Ge Xu，Xue Zhao， Hong bo Qi，Ting Li Han， Hua Zhang，Philip N. Baker．The effects of gestational diabetes mellitus with maternal age between 35 and 40 years on the metabolite profiles of plasma and urine. BMC Pregnancy Childbirth. 2022 Mar 2;22(1):174. doi: 10.1186/s12884-022-04416-5. PMID: 35236326; PMCID: PMC8892719. (IF=3.105)
7. Hongmei Zhou , Hong Ling , Yunlong Li , Xuejun Jiang , Shuqun Cheng , Golamaully Mohammad Zubeir , Yinyin Xia , Xia Qin , Jun Zhang , Zhen Zou , Chengzhi Chen. Downregulation of beclin 1 restores arsenite-induced impaired autophagic flux by improving the lysosomal function in the brain. Ecotoxicol Environ Saf. 2022 Jan 1;229:113066.(IF=7.129)
8. Jun Diao#, Yinyin Xia#, Xuejun Jiang#, Jingfu Qiu, Shuqun Cheng, Junhao Su, Xinhao Duan, Min Gao, Xia Qin, Jun Zhang, Jingchuan Fan, Zhen Zou*, Chengzhi Chen*. Silicon dioxide nanoparticles induced neurobehavioral impairments by disrupting microbiota-gut-brain axis. Journal of nanobiotechnology. 2021;19(1):174. Epub 2021/06/12. (IF=10.44)
9. Ting Zhang#, Wen-Rong Jiang#, Yin-Yin Xia, Toby Mansell, Richard Saffery, Richard D Cannon, Jamie De Seymour, Zhen Zou, Ge Xu, Ting-Li Han*, Hua Zhang*, Philip N Baker. Complex patterns of circulating fatty acid levels in gestational diabetes mellitus subclasses across pregnancy. Clinical Nutrition. 2021：:S0261-5614(21)00073-X. （IF=6.36）
10. Yu-Ting Chen#; Ting Zhang#; Chang Chen#; Yin-Yin Xia*; Ting-Li Han; Xu-Yang Chen; Xiao-Ling He; Ge Xu; Zhen Zou; Hong-Bo Qi; Hua Zhang; Benjamin B Albert; John Colombo; Philip N Baker; Associations of early pregnancy BMI with adverse pregnancy outcomes and infant neurocognitive development, Scientific Reports, 2021, 11(1): 3793. （IF=3.998）
11. Benjamin B Albert#; José G B Derraik#; Yin-Yin Xia*; Tom Norris; Ting Zhang; Ting-Li Han; Chen Chang; Angela Rowan; Sophie Gallier; Renato T Souza; Judith J Hammond; Wei Zhou; Hua Zhang; Hong-Bo Qi; Philip N Baker; Supplementation with milk enriched with complex lipids during pregnancy: a double-blind randomized controlled trial, PLoS One, 2021, 16(2): e0244916. （IF=2.74）
12. Harper Alexander, Baker Philip N., Xia Yinyin, Kuang Tao, Zhang Hua, Chen Yingxin, Han Ting-Li, Gulliver John*. Development of spatiotemporal land use regression models for PM2.5 and NO2 in Chongqing, China, and exposure assessment for the CLIMB study, Atmospheric Pollution Research, 2021,12(7):101096. （IF=4.352）
13. Dong Luo, Tao Kuang, Ying-Xin Chen, Yong-Hong Huang*, Hua Zhang, Yin-Yin Xia. Air pollution and pregnancy outcomes based on exposure evaluation using a land use regression model: A systematic review, Taiwan J Obstet Gynecol, 2021,60(2):193-215. （IF=1.51）
14. Rui-Yuan Zhang#, Jie-Bai Tu, Rui-Tu Ran, Wen-Xuan Zhang, Qiang Tan, Ping Tang, Tao Kuang, Shu-Qun Cheng, Cheng-Zhi Chen, Xue-Jun Jiang, Chang Chen, Ting-Li Han, Ting Zhang, Xian-Qing Cao, Bin Peng, Hua Zhang, Yin-Yin Xia, Using the Metabolome to Understand the Mechanisms Linking Chronic Arsenic Exposure to Microglia Activation, and Learning and Memory Impairment，Neurotoxicity Research, 2020, 39(3):720-739（IF=2.992）
15. Rui-Yuan Zhang#, Lan Wang#, Wei Zhou, Qi-Mei Zhong, Chao Tong, Ting Zhang, Ting-Li Han, Lian-Rong Wang, Xin Fan, Yan Zhao, Rui-Tu Ran, Yin-Yin Xia*, Hong-Bo Qi, Hua Zhang, Tom Norris , Philip Baker，Richard Saffery, Measuring maternal body composition by biomedical impedance can predict risk for gestational diabetes mellitus: a retrospective study among 22,223 women，J Matern Fetal Neonatal Med, 2020: (IF=1.737)
16. Ting Zhang#, Yinyin Xia#, Ting-Li Han*, Hua Zhang*, Philip Baker, Five serum fatty acids are associated with subclinical hypothyroidism in a Chinese pregnant population, Sci Rep, 2020. 10（1）: 6743 .(IF=4.011)
17. Tom Norris, Renato Souza, Yinyin Xia*, Ting Zhang, Angela Rowan, Sophie Gallier, Hua Zhang, Hongbo Qi, Philip Baker, Effect of supplementation of complex milk lipids in pregnancy on fetal growth: results from the Complex Lipids in Mothers and Babies (CLIMB) randomized controlled trial, J Matern Fetal Neonatal Med, 2019:1-10. (IF=1.569)
18. Yang Yang, Yanqiang Yin, Xuyang Chen, Chen Chang*, Yinyin Xia, Hongbo Qi, Philip Baker, Hua Zhang, Ting-Li Han*, Evaluating different extraction solvents for GC-MS based metabolomic analysis of the fecal metabolome of adult and baby giant pandas, Sci Rep, 2019,9(1):12017. (IF=4.122)
19. Xue Zhao, Yinyin Xia#, Hua Zhang*, Philip Baker, Norris Tom, Birth weight charts for a Chinese population: an observational study of routine newborn weight data from Chongqing, BMC Pediatr, 2019,19(1):426. (IF=1. 909)
20. Kai Yang, Xuejun Jiang, Shuqun Cheng, LuLu Bai, Yinyin Xia, Chengzhi Chen, Pan Meng, Jing Wang, Chunlin Li, Qianghu Tang, Xianqing Cao, Baijie Tu* , Synaptic dopamine release is positively regulated by SNAP-25 that involves in benzo[a]pyrene-induced neurotoxicity, chemosphere,2019 237:124378(IF=5.788)
21. Ting-Ting Mo#, Hua Dai#, Hang Du#, Rui-Yuan Zhang, Ke-Ping Chai, Yao An , Ji-Ji Chen , Jun-Ke Wang , Zi-Jin Chen , Cheng-Zhi Chen, Xue-Jun Jiang, Rong Tang , Li-Ping Wang , Qiang Tan, Ping Tang , Xin-Yu Miao, Pan Meng, Long-Bin Zhang, Shu-Qun Cheng*, Bin Peng, Bai-Jie Tu, Ting-Li Han, Yin-Yin Xia, Philip Baker, Gas chromatography-mass spectrometry based metabolomics profile of hippocampus and cerebellum in mice after chronic arsenic exposure, Environ Toxicol，2019. 34(2):103-111. (IF=1. 983)
22. Xuyang Chen, Jamie V. de Seymour, Ting-Li Han, Yinyin Xia, Chang Chen, Ting Zhang, Hua Zhang, Philip Baker, Metabolomic biomarkers and novel dietary factors associated with gestational diabetes in China, Metabolomics, 2018, 14(11):149. (IF=3.167)
23. Jing Wang, Chun-Lin Li, Bai-Jie Tu, Kai Yang, Ting-Ting Mo, Rui-Yuan Zhang, Shu-Qun Cheng, Cheng-Zhi Chen, Xue-Jun Jiang, Ting-Li Han, Bin Peng, Philip N. Baker, Yin-Yin Xia*, Intergrated epigenetics, transcriptomics and metabolomics to analyze the mechanism of Benzo[a]pyrene neurotoxicity in hippocampus, Toxicological Science, 2018, 166(1):65-81（IF=4.181）
24. Lulu Bai, Qianghu Tang, Zhen Zou, Pan Meng, Baijie Tu, Yinyin Xia, Shuqun Cheng, Lina Zhang, Kai Yang, Shaoyu Mu, Xuefeng Wang, Xia Qin, Bo Lv, Xianqing Cao, Qizhong Qin, Xuejun Jiang*, Chengzhi Chen*, m6A demethylase FTO regulates dopaminergic neurotransmission deficits caused by arsenite，Toxicological Science, 2018（IF=4.181）
25. Qianghu Tang, Lulu Bai, Zhen Zou, Pan Meng, Yinyin Xia, Shuqun Cheng, Shaoyu Mu, Jianrong Zhou, Xuefeng Wang, Xia Qin, Xianqing Cao, Xuejun Jiang*, Chengzhi Chen*, Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure，Neurotoxicology，2018, 67:27-36（IF=3.076）
26. Chao Tong#, Li Wen#, Yinyin Xia, Pamela Leong, Lan Wang, Xin Fan, Ting-li Han, Jeffrey M Craig, Philip Baker, Richard Saffery#, Hongbo Qi#*, Protocol for a longitudinal twin birth cohort study to unravel the complex interplay between early-life environmental and genetic risk factors in health and disease: the Chongqing Longitudinal Twin Study (LoTiS), BMJ Open, 2018, 8(2): e017889 （IF=2.413）
27. Thibaut D.J. Delplancke#, Jamie V de Seymour#, Chao Tong#, Karolina Sulek, Yinyin Xia, Hua Zhang, Ting-Li Han*, Philip N. Baker, Analysis of Sequential Hair Segments Reflects Changes in the Metabolome across the Trimesters of Pregnancy, Scientific Reports, 2018, 8(1): 36（IF=4.122）
28. Chunlin Li, Jing Wang, Qiuping Su, KaiYang, Chengzhi Chen, XueJun Jiang, Ting-Li Han, Shuqun Cheng, Tingting Mo, Ruiyuan Zhang, Bin Peng, Yuming Guo, Philip N. Baker, Baijie Tu*, Yinyin Xia*, Postnatal Subacute Benzo(A)Pyrene Exposure Caused Neurobehavioral Impairment and Metabolomic Changes of Cerebellum in the Early Adulthood Period of Sprague-Dawley Rats, Neurotoxicity Research, 2017, 33(4):812-823（IF=3.186）
29. Jianlin Zhao, Nan Shan, Xiaochang Yang, Qin Li, Yinyin Xia, Hua Zhang, Hongbo Qi*, Effect of second child intent on delivery mode after Chinese two child policy implementation: a cross sectional and prospective observational study of nulliparous women in Chongqing, BMJ Open, 2017, 7(12): e018823 （IF=2.413）
30. Shuai Huang, TingTing Mo, Tom Norris, Si Sun, Ting Zhang, Ting-Li Han, Angela Rowan, YinYin Xia*, Hua Zhang, Hongbo Qi*, Philip N. Baker*, The Climb (Complex Lipids In Mothers and Babies) Study: Protocol for a Multicentre, Three-Group, Parallel Randomised Controlled Trial to Investigate the Effect of Supplementation of Complex Lipids in Pregnancy, on Maternal Ganglioside Status and Subsequent Cognitive Outcomes in the Offspring, BMJ Open, 2017, 7(10): e016637 （IF=2.413）
31. Xiang Feng, Liyuan Zhou, Xun Mao, Chao Tong, Xuyang Chen, Diqi Zhao, Philip N. Baker, Yinyin Xia, Hua Zhang，Association of a Reduction of G‑protein Coupled Receptor 30 Expression and the Pathogenesis of Preeclampsia, Molecular Medicine Reports, 2017, 16(5): 5997-6003 （IF=1.922）
32. Yi Wu, Xuejun Jiang, Kai Yang, Yinyin Xia, Shuqun Cheng, Qianghu Tang, Lulu Bai, Jingfu Qiu*, Chengzhi Chen*, Inhibition of a-Synuclein Contributes to the Ameliorative Effects of Dietary Flavonoids Luteolin on Arsenite-induced Apoptotic Cell Death in the Dopaminergic PC12 Cells, Toxicology Mechanisms and Methods, 2017, 27(8): 598-608 （IF=1.595）
33. Kai Yang，Xuejun Jiang，Qiuping Su，Jing Wang，Chunlin Li，Yinyin Xia，Shuqun Cheng，Qizhong Qin，Xianqing Cao，Chengzhi Chen*，Baijie Tu*，Disruption of Glutamate Neurotransmitter Transmission Is Modulated by SNAP-25 in Benzo[a]pyrene-induced Neurotoxic Effects, Toxicology, 2017, 384: 11-22 （IF=3.582）
34. Tingting Mo, Si Sun, Yongyi Wang, Dong Luo, Bin Peng, Yinyin Xia*, Mercury Poisoning Caused by Chinese Folk Prescription (CFP): a Case Report and Analysis of both CFP and Quackery, Medicine (Baltimore), 2016, 95(44): e5162 （IF=2.133）
35. Yinyin Xia ，Yubing Ding ，Xueqing Liu ，Xuemei Chen ，Shuqun Cheng ，Lianbing Li ，Mingfu Ma ，Junlin He* ，Yingxiong Wang* ， Racial/ethnic disparities in human DNA methylation，Biochim Biophys Acta, 2014, 1846(1): 258-262（IF=7.584）
36. Yinyin Xia ，Yubing Ding ，Xueqing Liu ，Xuemei Chen ，Shuqun Cheng ，Lianbing Li ，Mingfu Ma ，Junlin He* ，Yingxiong Wang* ，Allelic methylation status of CpG islands on chromosome 21q in patients with Trisomy 21，Molecular Medicine Reports, 2014, 9(5):1681-1688（IF=1.484）
37. Shuqun Cheng# ，Yinyin Xia # ，Junlin He ，Xueqing Liu ，Xuemei Chen ，Yubin Ding ，Yingxiong Wang ，Bing Peng ，Baijie Tu* ，Neurotoxic effect of subacute benzo(a)pyrene exposure on gene and protein expression in Sprague-Dawley rats，Environmental toxicology and pharmacology，2013, 36(2):648-658（IF=2.005）
38. Yongyi Wang ，Jian Xue ，Shuqun Cheng ，Yubin Ding ，Junlin He ，Xueqing Liu ，Xuemei Chen ，Yingxiong Wang ，Xiangyu Feng ，Yinyin Xia* ，The relationship between manganism and the workplace environment in China，International journal of occupational medicine and environmental health，2012, 25(4):501-505（IF=1.305）
39. Yinyin Xia ，Shuqun Cheng ，Junlin He ，Xueqing Liu ，Yan Tang ，Haiyan Yuan ，Lijun He ，Tao Lu ，Baijie Tu* ，Yingxiong Wang* ，Effects of subchronic exposure to benzo[a]pyrene (B[a]P) on learning and memory, and neurotransmitters in male Sprague-Dawley rat，Neurotoxicology，2011, 32(2):188-198（IF=3.096）
40. Chongying Qiu, Shuqun Cheng, Yinyin Xia, Bin Peng, Baijie Tu*, The effect of occupational exposure to benzo[a]pyrene on neurobehavioral function in coke oven workers，American journal of industrial medicine，56(3)，347-355，2013 （IF=1.973）
41. Yubin Ding, Chunlan Long, Xueqing Liu, Xuemei Chen, Liangrui Guo, Yinyin Xia, Junlin He*, Yingxiong Wang*, 5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes，PloS one，7(9)，e45364，2012（IF=3.73）
42. Qian Tang, Yinyin Xia, Shuqun Cheng, Baijie Tu*, Modulation of behavior and glutamate receptor mRNA expression in rats after sub-chronic administration of benzo(a)pyrene，Biomedical and environmental sciences，24(4)，408-414，2011（IF=1.345）
43. Chongying Qiu, Shuqun Cheng, Yinyin Xia, Bin Peng, Qian Tang, Baijie Tu*, Effects of subchronic benzo(a)pyrene exposure on neurotransmitter receptor gene expression in the rat hippocampus related with spatial learning and memory change，Toxicology，289(2-3)，83-90，2011（IF=3.681）
44. Chengzhi Chen, Yan Tang, Shuqun Cheng, Xuejun Jiang, Youbin Qi, Yinyin Xia, Qian Tang, Baijie Tu*, New candidate proteins for benzo(a)pyrene-induced spatial learning and memory deficits，The Journal of toxicological sciences，36(2)，163-171，2011 (IF=1.522)
45. Yinyin Xia，Ping Zhan*, Yang Wang. Effects of nonylphenol on brain gene expression profiles in F1 generation rats. Biomedical and Environmental Sciences 2008.21:1-6 (IF=0.675)
