Faculty & Research

College of Public Health -- PEI Desheng

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PERSONAL INFORMATION

Name: Pei, De-Sheng

Gender: Male

Title: Prof.

Position: Lab head, PI

 

CONTACT INFORMATION

Email: peids@cqmu.edu.cn

 

EDUCATION EXPERIENCE

2003.9-2006.6: PhD, Genetics, Institute of Hydrobiology, Chinese Academy of Sciences


WORKING EXPERIENCE

2021.09 to present: Professor and PhD supervisor, Chongqing Medical University

2012.08-2021.09: Professor and PhD supervisor, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences; Dean of Environmental and Health Research Center, Deputy Director of Key Laboratory of Reservoir Aquatic Environment of Chinese Academy of Sciences

2011.02-2013.02: Harvard University, Research Fellow

2009.02-2011.02: Northeastern University (Boston), Senior Postdoctoral Fellow

2006.06-2009.02: Assistant professor, Institute of Hydrobiology, Chinese Academy of Sciences


RESEARCH INTERESTS

Prof. Pei mainly focuses on developing animal models for human diseases, studying gut bacteria function using germ-free fish models, and elucidating the toxicity effects of environmental pollutants.


HONOUR & AWARDS

1. Hundred Talents Program (Class A) of the Chinese Academy of Sciences

2. Chongqing Young and Middle-aged Expert with Outstanding Contribution

3. Chongqing Leading Talent in Science and Technology Innovation

4. Chongqing Postdoctoral Innovation Mentorship Studio

5. First Prize of Chongqing Industry-University-Research Cooperation Innovation Achievement Award


PUBLICATIONS

1. Liu L, Duan JJ, Wei XY, Hu H, Wang YB, Jia PP, Pei DS*. Generation and application of a novel high-throughput detection based on RPA-CRISPR technique to sensitively monitor pathogenic microorganisms in the environment. Science of the Total Environment. 2022, 838(2):156048.

2. Luo JJ#, Liu P#, Lu C, Bian W, Su D, Zhu C, Xie SL, Pan Y, Li N, Cui W, Pei DS*, Yang X*. Stepwise crosstalk between aberrant Nf1, Tp53 and Rb signalling pathways induces gliomagenesis in zebrafish. Brain. 2020, 144(2): 615–635.

3. T.Y Suman#, Jia PP#, Li WG#, Junaid M, Xin GY, Wang Y, Pei DS*. Acute and chronic effects of polystyrene microplastics on brine shrimp: First evidence highlighting the molecular mechanism through transcriptome analysis. Journal of Hazardous Materials. 2020, 400:123220.

4. Hamid N, Junaid M, Manzoor R, Jia PP, Pei DS*. Prioritizing Phthalate Esters (PAEs) using experimental in vitro/vivo toxicity assays and computational in silico approaches. Journal of Hazardous Materials. 2020, 398:122851.

5. Wang Y, Hamid N, Deng S, Jia PP, Pei DS*. Individual and combined toxicogenetic effects of microplastics and heavy metals (Cd, Pb, and Zn) perturb gut microbiota homeostasis and gonadal development in marine medaka (Oryzias melastigma). Journal of Hazardous Materials. 2020, 397:122795.

6. Hamid N#, Junaid M#, Pei DS*. Individual and combined mechanistic toxicity of Sulfonamides and their implications for ecological risk assessment in the Three Gorges Reservoir Area (TGRA), China. Journal of Hazardous Materials. 2019, 382:121106.

7. Junaid M, Wang Y, Hamid N, Deng S, Li WG, Pei DS*. Prioritizing selected PPCPs on the basis of environmental and toxicogenetic concerns: a toxicity estimation to confirmation approach. Journal of Hazardous Materials. 2019, 380:120828.

8. Pei DS*, Jia PP, Luo JJ, Liu W, Strauss RP*. AP endonuclease 1 (Apex1) influences brain development linking oxidative stress and DNA repair. Cell Death & Disease. 2019, 10:348.

9. Deng S#, Fu A#, Junaid M, Wang Y, Yin Q, Fu C, Liu L, Su DS, Bian WP, Pei DS*. Nitrogen-doped graphene quantum dots (N-GQDs) perturb redox-sensitive system via the selective inhibition of antioxidant enzyme activities in zebrafish. Biomaterials. 2019, 206:61-72

10. Pei DS, Yang XJ, Liu W, Guikema J, Schrader C, Strauss P*. A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase ß. Nucleic Acids Research. 2011, 39(8):3156-65.