PERSONAL INFORMATION
Name: Hongmei Zhang
Professional title: Professor, Chief physician, Doctoral supervisor
Profile: Academician of International College of Dentists XIII-China, Senior visiting scholar of the University of Chicago, Committee member of the Professional Committee of Chinese Children's Stomatology, Standing member of China Oral Health Big Data Specialist Alliance, Director of ChongQing Stomatological Association，Vice chairman of Preventive and Children's Stomatology Specialty Committee of Chongqing Stomatological Association, Committee member of Oral Biomedical Specialty Committee, Specialist of the Sickness retirement identification of Chongqiong institutions and agencies. Mainly engaged in medical, teaching and research work in children's dentistry and preventive dentistry. I am a professional physician with good quality and have accumulated rich clinical, teaching and research experience.
CONTACT INFORMATION
Tel；E-mail: 13983867373; zhm5025@aliyun.com
EDUCATION EXPERIENCE
(1) 2010.9–2015.7, Chongqing Medical University, Clinical Laboratory Diagnostics, PhD
(2) 2005.9–2008.7, Chongqing Medical University, Oral Clinical Medicine,;
(3) 1997.9–2000.7, Chongqing Medical University, Clinical medicine,;
(4) 1992.9–1995.7, Luzhou Medical College, Oral medicine,;
WORKING EXPERIENCE
(1) 2019.10-up to now, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Professor;
(2) 2017.11-up to now, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Chief physician;
(3) 2013.9-up to now, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Associate professor;
(4) 2013.3-2014.3, University of Chicago, Centre of Molecular Medicine, Senior Visiting Scholar;
(5) 2009.10-2017.11, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Associate Chief Physician;
(6) 2008.7-2013.9, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Lecturer;
(7) 2003.9-2009.10, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Attending Physician;
(8) 1998.6-2003.9, Stomatological Hospital of Chongqing Medical University, College of Dentistry, Physician;
(9) 1995.7-1998.6, Chongqing West Suburban Hospital, Department of stomatology, Physician.
RESEARCH FIELD
1.Bone morphogenetic protein 9 (BMP9) and other cytokines promote regeneration and osteogenic repair of tooth-derived stem cells in tissue defects;
2.Immune-related research in the inflammatory microenvironment;
3.Research on the prevention and treatment of oral diseases in children.
PUBLICATIONS
Articles:
1. Hongmei Zhang, Jinhua Wang, Fang Deng, Enyi Huang, Zhengjian Yan, Zhongliang Wang, Youlin Deng, Qian Zhang, Zhonglin Zhang, Jixing Ye, Min Qiao, Ruifang Li, Jing Wang, Qiang Wei, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Tong-Chuan He*, Feng Deng*. Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials. 2015 (39): 145-154.
2. Jun Deng, Yingying Tang, Qing Zhang, Chao Wang, Min Liao, Ping Ji, Jinlin Song,Gaoxing Luo, Luo Chen, Xiaohong Ran, Ziming Wei, Liwen Zheng, Ruyi Dang,Xiang Liu, Hongmei Zhang*, Yu Shrike Zhang*, Ximu Zhang*, and Hong Tan. A Bioinspired Medical Adhesive Derived from Skin Secretion of Andriasdavidianus for Wound Healing. Advanced Functional Materials, 2019, 29(31).
3. Xia Huang, Qiuman Chen, Wenping Luo, Mikhail Pakvasa, Yuxin Zhang, Liwen Zheng, Shuang Li, Zhuohui Yang, Huan Zeng, Fang Liang, Fugui Zhang, Daniel A. Hu, Kevin H. Qin, Eric J. Wang, David S. Qin, Russell R. Reid, Tong-Chuan He, AravindAthiviraham, Mostafa El Dafrawy, and Hongmei Zhang*,SATB2: A versatile transcriptional regulator of craniofacial and skeleton development, neurogenesis and tumorigenesis, and its applications in regenerative medicine. Genes & Diseases, 2022,9(1):95-107
4. Chen Q, Zheng L, Zhang Y, Huang X, Wang F, Li S, Yang Z, Liang F, Hu J, Jiang Y, Li Y, Zhou P, Luo*, Zhang H*. Special AT-rich sequence-binding protein 2 (Satb2) synergizes with Bmp9 and is essential for osteo/odontogenic differentiation of mouse incisor mesenchymal stem cells. CellProlif. 2021, 54(4): e13016.
5. Cheng Q, Lin J, Chen Q, Zheng L, Tang Y, Wang F, Huang X, Zhang Y, Li S, Yang Z, Zhou P, He TC, Luo W*, Zhang H*. Role of Special AT-Rich Sequence-Binding Protein 2 in the Osteogenesis of Human Dental Mesenchymal Stem Cells. Stem Cells Dev. 2020,29(16):1059-1072.
6. Huang X, Wang F, Zhao C, Yang S, Cheng Q, Tang Y, Zhang F, Zhang Y, Luo W, Wang C, Zhou P, Kim S, Zuo G, Hu N, Li R, He TC*, Zhang H*.Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice. Stem Cells Dev. 2019,28(10):683-694.
7. Liwen Zheng, Haolin Wang, Li Mei, Qiuman Chen, Yuxin Zhang, Hongmei Zhang*.Artificial intelligence in digital cariology: a new tool for the diagnosis of deep caries and pulpitis using convolutional neural networks. AnnTransl Med. 2021, 9(9): 763.
8. Feilong Wang,Ying Jiang,Sheng Yang,Qin Liu,Juhong Lin*,Hongmei Zhang*.Associations between the NOGGIN rs227731 polymorphism and NSCL/P risk may be associated with ethnicities: A meta-analysis. Birth Defects Res. 2017,41(5):1725-1735.
9. Wenping Luo, Hongmei Zhang, Yan Zhang, Panpan Liang, Xiaojie Wang , Jing Ma, Dongmei Tan, Yi Tan, Jinlin Song , Ping Ji, Tianyu Zhao*.L-type amino acid transporter 1 promotes proliferation and invasion of human chorionic trophoblast and choriocarcinoma cells through mTORC1. Am J Transl Res. 2020,12(10):6665-6681.
10. Yihan Li, Annie Shrestha,Hongmei Zhang,Lingjie Li, Dize Li, Tiwei Fu , Jinlin Song, Ping Ji, Yuanding Huang*, Tao Chen*.Impact of diabetes mellitus simulations on bone cell behavior through in vitro models. J Bone Miner Metab. 2020,38(5):607-619.
11. Yu X, He D, Zhang X, Zhang H, Song J, Shi D, Fan Y, Luo G, Deng J.Surface-Adaptive and Initiator-Loaded Graphene as a Light-Induced Generator with Free Radicals for Drug-Resistant Bacteria Eradication. ACSAppl Mater Interfaces. 2019,16,11(2):1766-1781.
12. Wenping Luo, Linghuan Zhang, Bo Huang, Hongmei Zhang, Yan Zhang, Fugui Zhang, Panpan Liang, Qiuman Chen, Qianyu Cheng, Dongmei Tan, Yi Tan, Jinlin Song, Tianyu Zhao, Rex C. Haydon, Russell R. Reid, Hue H Luu, Michael J. Lee, Mostafa El Dafrawy, Ping Ji, Tong-Chuan He* and Liming Gou*.BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCs) requires Wnt/β-catenin signaling activity.Journal of Cellular and Molecular Medicine. 2021),25(5):2666-2678;
13. Ximu Zhang , Chao Wang, Min Liao, Lina Dai, Yingying Tang,Hongmei Zhang, Phil Coates , FarshidSefat, Liwen Zheng, Jinlin Song, Zhuo Zheng, Dan Zhao , Maobin Yang ,Wei Zhang*, Ping Ji.Alignedelectrospun cellulose scaffolds coated with rhBMP-2 for both in vitro and in vivo bone tissue engineering.Carbohydr. Polym, 2019,213:27-38,
14. Hongmei Zhang, Zhengjian Yan, Melissa Li, Michael Peabody, and Tong-Chuan He* . CRISPR Clear? Dimeric Cas9-Fok1 Nucleases Improve Genome-Editing Specificity.Genes & Diseases. 2014(1): 6-7.
15.Ningning Wu, Hongmei Zhang, Fang Deng, Ruidong Li, Wenwen Zhang, Xian Chen, Sheng Wen, Ning Wang, Junhui Zhang, Liangjun Yin, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Di Wu, Jixing Ye, Youlin Deng, Ke Yang, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He*. Overexpression of Ad5 Precursor Terminal Protein (pTP) Accelerates Recombinant Adenovirus Packaging and Amplification in HEK-293 Packaging Cells. Gene Therap . 2014(21), 629–637.
16. Sheng Wen, Hongmei Zhang, Yasha Li, Ning Wang, Wenwen Zhang, Ke Yang, Ningning Wu, Xian Chen, Fang Deng, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Tong-Chuan He*, and Guanghui Wei*. Characterization of Constitutive Promoters for piggyBac Transposon-mediated Stable Transgene Expression in Mesenchymal Stem Cells (MSCs). PLOS ONE. 2014, 9(4),e94397.
17.Jinhua Wang, Hongmei Zhang, Wenwen Zhang, Enyi Huang, Ning Wang, Ningning Wu, Sheng Wen, Xian Chen, Zhan Liao, Fang Deng, Liangjun Yin, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Feng Deng*. BMP9 Effectively Induces Osteo/Odontoblastic Differentiation in the Reversibly Immortalized Stem Cells from Mouse Dental Apical Papilla (SCAPs). Stem Cells and Development. 2014, 23(12): 1405-1416.
18. Fugui Zhang, Yong Li, Hongmei Zhang, Enyi Huang, Lina Gao, WenpinLuo, Qiang Wei, Jiaming Fan, Dongzhe Song, Junyi Liao, Yulong Zou, Feng Liu, Jianxiang Liu, Jiayi Huang, Dan Guo, Chao Ma, Xue Hu, Li Li, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Tingting Wu, Hue H. Luu, Rex C. Haydon, Jinlin Song, Tong-Chuan He*, and Ping Ji* . Anthelmintic Mebendazole Enhances Cisplatin’s Effect on Suppressing Cell Proliferation and Promotes Differentiation of Head and Neck Squamous Cell Carcinoma (HNSCC). Oncotarget. 2017, 8 (8):12968-12982.
19. Yanhong Gao*, Enyi Huang, Hongmei Zhang, Jinhua Wang, Ningning Wu, Xian Chen, Ning Wang, Sheng Wen, Guoxin Nan, Fang Deng, Zhan Liao, Di Wu, Bosi Zhang, Junhui Zhang, Rex C. Haydon, Hue H. Luu, Lewis L Shi, and Tong-Chuan He* . Crosstalk between Wnt/β-Catenin and Estrogen Receptor Signaling Synergistically Promotes Osteogenic Differentiation of Mesenchymal Progenitor Cells.PLoS One. 2013,8(12),:e82436- e82436.
20. Ke Yang,Xin Wang, Hongmei Zhang,Zhongliang Wang, Guoxin Nan,Yasha Li,Fugui Zhang, Maryam K Mohammed, Rex C Haydon,Hue H Luu,Yang Bi*,and Tong-Chuan He*. The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Laboratory Investigation, 2015,:1–21.
21. Lin Jiang, Jinlin Song, Xiaolei Hu, Hongmei Zhang, Enyi Huang,Yan Zhang, Feng Deng*, Xiaomian Wu*.The Proteasome Inhibitor Bortezomib Inhibits Inflammatory Response of Periodontal Ligament Cells and Ameliorates Experimental Periodontitis in Rats. Journal of Periodontology. 2017,88 (5): 473-483
22. Fugui Zhang, Jinglin Song, Hongmei Zhang,Enyi Huang, Dongzhe Song, Viktor Tollemar, Jing Wang, Jinhua Wang, Maryam Mohammed, Qiang Wei, Jiaming Fan, Junyi Liao, Yulong Zou, Feng Liu, Xue Hu, Xiangyang Qu, Liqun Chen, Xinyi Yu, Hue H. Luu, Michael J. Lee, Tong-Chuan He*, and Ping Ji* . Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering. Genes&Diseases. 2016.3(4):263-276.
23. Chen Zhao, Ningning Wu, Fang Deng, Hongmei Zhang, Ning Wang, Wenwen Zhang, Xian Chen, Sheng Wen, Junhui Zhang, Liangjun Yin, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Di Wu, Jixing Ye, Youlin Deng, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Weike Si*, and Tong-Chuan He* .Adenovirus-Mediated Gene Transfer in Mesenchymal Stem Cells Can be Significantly Enhanced by the Cationic Polymer Polybrene. PLoS One. 2014,9(3), e92908-e92908.
24 Ning Wang#, Wenwen Zhang#, Jing Cui, Hongmei Zhang, Xiang Chen, Ruidong Li, Ningning Wu, Xian Chen, Sheng Wen, Junhui Zhang, Liangjun Yin, Fang Deng, Zhan Liao, Zhonglin Zhang, Qian Zhang, Zhengjian Yan,Wei Liu, Jixing Ye, Youlin Deng, Zhongliang Wang, Min Qiao, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Houjie Liang*, and Tong-Chuan He*.The piggyBac Transposon-Mediated Expression of SV40 T Antigen Efficiently Immortalizes Mouse Embryonic Fibroblasts (MEFs). PLoS One. 2014, 9(5): e97316-e97316.
25. Xiang Chen, Jing Cui, Zhengjian Yan, Hongmei Zhang, Xian Chen, Ning Wang, Palak Shah, Fang Deng, Chen Zhao, Nisha Geng, Melissa Li, Sahitya K. Denduluri, Rex C. Haydon, Hue H. Luu, Russell R. Reid, and Tong-Chuan He .Sustained high level transgene expression in mammalian cells mediated by the optimized piggyBac transposon system. Genes & Diseases. 2015, 2(1):96-105.
26. Jing Ma, Yan Zhang, Jun Wang, Tianyu Zhao, Ping Ji, Jinlin Song, Hongmei Zhang, Wenping Luo. Proliferative effects of gamma-amino butyric acidon oral squamous cell carcinoma cells are associated withmitogen-activated protein kinase signaling pathways. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE .2016, 38(1):305-11.
27.Wei Shui, Wenwen Zhang, Liangjun Yin, Guoxin Nan, Zhan Liao, Hongmei Zhang, Ning Wang, Ningning Wu, Xian Chen, Sheng Wen, Yunfeng He, Fang Deng, Junhui Zhang, Hue H. Luu, Lewis L Shi, Zhenming Hu, Rex C. Haydon, James Mok, and Tong-Chuan He .Characterization of scaffold carriers for BMP9-transduced osteoblastic progenitor cells in bone regeneration. Journal of Biomedical Materials Research: Part A. 2013,102(10):3429-3438.
28. Wenwen Zhang, Hongyu Zhang, Ning Wang, Chen Zhao, Hongmei Zhang, Fang Deng, Ningning Wu, Yunfeng He, Xian Chen, Junhui Zhang, Sheng Wen, Zhan Liao, Qian Zhang, Zhonglin Zhang, Wei Liu, Zhengjian Yan, Hue H. Luu, Rex C. Haydon, Lan Zhou, and Tong-Chuan He.Modulation of β-Catenin Signaling by the Inhibitors of MAP Kinase, Tyrosine Kinase, and PI3-Kinase Pathways.International Journal of Medical Sciences.2013,10(13):1888-1898.
29. Xian Chen, Gaurav Luther, Wenwen Zhang, Guoxin Nan, Eric R. Wagner, Zhan Liao, Ningning Wu, Hongmei Zhang, Ning Wang, Sheng Wen, Yunfeng He, Fang Deng, Junhui Zhang, Di Wu, Bosi Zhang, Rex C. Haydon, Lan Zhou, Hue H. Luu, and Tong-Chuan He.The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cellular Physiology and Biochemistry. 2013,32(4):1083-96.
30.Ning Wang, Hongyu Zhang, Bing-Qiang Zhang, Wei Liu, Zhonglin Zhang, Min Qiao, Hongmei Zhang, Fang Deng, Ningning Wu, Xian Chen, Sheng Wen, Junhui Zhang, Zhan Liao, Qian Zhang, Zhengjian Yan, Liangjun Yin, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Houjie Liang*, and Tong-Chuan He* . Adenovirus-Mediated Efficient Gene Transfer into Cultured Three-Dimensional Organoids.PLoS One. 2014, 9(4):e93608-e93608.
31.Ruidong Li, Wenwen Zhang, Jing Cui, Wei Shui, Liangjun Yin1, Yang Wang, Hongyu Zhang, Ning Wang, Ningning Wu, Guoxin Nan, Xian Chen, Sheng Wen, Fang Deng, Hongmei Zhang, Guolin Zhou, Zhan Liao, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Den, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Zhong-Liang Deng*.Targeting BMP9-Promoted Human Osteosarcoma Growth by Inactivation of Notch Signaling. Current Cancer Drug Targets. 2014,14:274-285.
32.Yuhan Kong, Hongyu Zhang, Xian Chen, Wenwen Zhang, Chen Zhao, Ning Wang, Ningning Wu, Yunfeng He, Guoxin Nan, Hongmei Zhang, Sheng Wen, Fang Deng, Zhan Liao, Di Wu, Junhui Zhang, Xinyue Qin, Rex C. Haydon, Hue H. Luu, Tong-Chuan He, and Lan Zhou .Destabilization of Heterologous Proteins Mediated by the GSK3β Phosphorylation Domain of the β-Catenin Protein. Cellular Physiology and Biochemistry. 2013,32(5):1187-99.
33.Ning Hu, Changdong Wang, Xi Liang, Liangjun Yin, Xiaoji Luo, Bo Liu, Hongyu Zhang, Wei Shui, Guoxin Nan, Ning Wang, Ningning Wu, Xian Chen, Yunfeng He, Sheng Wen, Fang Deng, Hongmei Zhang, Zhan Liao, Hue H. Luu, Rex C. Haydon, Tong-Chuan He, and Wei Huang . Inhibition of Histone Deacetylases Potentiates BMP9-Induced Osteogenic Signaling in Mouse Mesenchymal Stem Cells. Cellular Physiology and Biochemistry. 2013,32(2):486-498.
34.Jiye Zhang, Yaguang Weng, Xing Liu, Jinhua Wang, Wenwen Zhang, Stephanie H Kim, Hongyu Zhang, Ruidong Li, Yuhan Kong, Xiang Chen, Wei Shui, Ning Wang, Chen Zhao, Ningning Wu, Yunfeng He, Guoxin Nan, Xian Chen, Sheng Wen, Hongmei Zhang, Fang Deng, Lihua Wan, Hue H. Luu, Rex C. Haydon, Lewis L. Shi, Tong-Chuan He* and Qiong Shi* . Endoplasmic reticulum (ER) stress inducible factor cysteine-rich with EGF-like domains 2 (Creld2) is an important mediator of BMP9-regulated osteogenic differentiation of mesenchymal stem cells. PLOS One. 2013,8(9): e73086-e73086.
35.Joseph D. Lamplot*, Bo Liu*, Liangjun Yin, Wenwen Zhang, Zhongliang Wang, Gaurav Luther, Eric Wagner, Ruidong Li, Guoxin Nan, Wei Shui, Zhengjian Yan, Richard Rames, Fang Deng, Hongmei Zhang, Zhan Liao, Wei Liu, Junhui Zhang, Zhonglin Zhang, Qian Zhang, Jixing Ye, Youlin Deng, Min Qiao, Rex C. Haydon, Hue H Luu, Jovito Angeles, Lewis L. Shi, Tong-Chuan He#, and Sherwin H. Ho# . Reversibly Immortalized Mouse Articular Chondrocytes Acquire Long-Term Proliferative Capability while Retaining Chondrogenic Phenotype. Cell Transplantation. 2015,24(6):1053-1066.
36. YuhongWu, JuhongLin, HongmeiZhang*, Comparison of particle size and partial heavy metal content of white Portland cement with MTA. Journal of Huazhong University of Science and Technology (Medical Edition). 2015,44 (3):302-305.
37. Yan Wang, Juhong Lin, Hongmei Zhang*, Mingfang Liu. Experimental study on in vitro growth inhibition of three microorganisms by Portland hydromorphone, Journal of Chongqing Medical University,2013, 36(7): 801-804.
38. Qiao Liu, Juhong Lin, Dan Chen, Hongmei Zhang*, Wenzhu Ma, Xiaohui Xu, In vitro study of microleakage at the edges of fluorine-containing resin sealers and glass ionomer sealers. Journal of Chongqing Medical University. 2013, 38(1): 98-100.
39. Yongfeng Luo, Juhong Lin, Hongmei Zhang*, Scanning electron microscopy of the dentin surface after Carisolv chemical-mechanical decay, Laser Journal. 2012, 33(6): 62-64.
40. Jiang Lin, Lin Juhong, Wang Jinhua, Zhang Hongmei*, Zhou Zhi, Hu Yun, Wang Lin, Liu Qiao, Liu Yujia, Report of a sample survey on dental fluorosis in a 12-year-old population in Chongqing. Chongqing Medical Journal. 2010, 39 (10): 1237-1238.
41. Jiang Lin, Juhong Lin, Hongmei Zhang*. Clinical efficacy of domestic water-soluble propolis on the disinfection efficacy of infected root canals. Chongqing Medical Journal. 2009, 38(23): 2939-2940.
42. Jiang Lin, Juhong Lin, Hongmei Zhang*. In vitro inhibition of anaerobic bacteria in root canals by domestic water-soluble propolis. Journal of Chongqing Medical University. 2008,33(12):1516-1519.
43. Lin Jiang, Juhong Lin, Hongmei Zhang*. Cytotoxicity study of propolis and calcium hydroxide administered alone. Journal of Chongqing Medical University. 2007, 32(11): 1193-1196.
Project:
1. 2019.1-2022.12, General program-The National Natural Science Foundation of China, Study of the role of SATB2 in influencing BMP9-induced osteogenic differentiation of apical tooth papillae stem cells in an inflammatory microenvironment, 81870758, 570,000, Project director.
2. 2021.10-2024.9, The Natural Science Foundation of Chongqing, Study of the role of BMP9-GelMA-HMPs in regulating macrophage polarization in the inflammatory microenvironment, cstc2021jcyj-msxmX0560, 10,000, Project director
3. 2017.7-2020.7, Provincial level projects of Chongqing Science and Technology Commission, Study of the role of BMP9 in inducing osteogenic differentiation of stem cells from the apical papilla in an inflammatory microenvironment, cstc2017jcyjAX0020, 50,000, Project director.
4. 2020.9-2022.9, Joint Project of Chongqing Science and Technology Bureau and Chongqing Municipal Health and Health Commission, Research on the clinical application of intelligent diagnosis system of caries based on migration learning, 2021MSXM209, 50,000, Project director.
5. 2020.9-2022.9, Science and Technology Project of Chongqing Yubei District Science and Technology Bureau, Research on the application of a new system for intelligent diagnosis of oral tissue diseases based on deep learning, (2020) 86, 50,000, Project director.
6. 2016.1-2018.12, Provincial level projects of Chongqing Science and Technology Commission, Study on the establishment of data on children's oral health and the application of comprehensive oral disease intervention in Chongqing, cstc2015shmszx00012, 20,000, Project director.
7. 2014.7-2017.7, Provincial level projects of Chongqing Science and Technology Commission, Canonical Wnt signaling acts synergistically on BMP9-induced
osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs)，cstc2014jcyjA10010, 25,000, Project director.
8. 2014.7-2017.7, Chongqing Yubei District Science and Technology Commission subject, Study on the mechanism of bone formation protein 9 to promote the development of tooth apical tissue, (2014) 42, 10,000, Project director.
9. 2011.9-2014.9, Chongqing Health Bureau Project, Basic research of PORTLAND CEMENT for endodontic treatment and evaluation of its biological activity, 2011-2-190, 15,000, Project director.
10. 2010.1－2012.12, Chongqing Health Bureau Project, Basic Research on Minimally Invasive Technique of Carisolv for the Treatment of Dental Caries in Deciduous Teeth, 2009-2-154, 10,000, Project director.
Awards:
1. 2016, The establishment and comprehensive application of epidemiological database of caries in adolescent children in Chongqing (2015-J-3-59-R02), Third Prize of Chongqing Science and Technology Progress Award, number 2;
2. 2015, The establishment and comprehensive application of epidemiological database of caries in adolescent children in Chongqing, Second Prize of 2014 Medical Science and Technology Achievement of Chongqing municipal health an, number 2;
3. 2014-2015,“Outstanding Scientific and Technical Paper Award of Chongqing Medical University;
4. 2016, Chongqing Association for Science and Technology “Outstanding Academic Papers in Natural Sciences”;
5. 2018, Chongqing human resources and Social Security Bureau, Chongqing science and Technology Bureau “Advanced Individual of Chongqing Science and Technology System”;
6. 2020, Sichuan Association for Science and Technology, Chongqing Association for Science and Technology, “Excellent paper of the first Sichuan and Chongqing Science and Technology Academic Conference” 2nd Prize.
Patents:
1. Hongmei Zhang, Ximu Zhang, Feilong Wang, Lin Jiang. Manual nickel-titanium instrumentation assist device for pediatric endodontics, 2020, Patent for Utility Model, ZL201922116182.X
2. Hongmei Zhang, Ximu Zhang, Feilong Wang, Lin Jiang. Manual nickel-titanium instrumentation assist device for pediatric endodontics. Anti-swallowing endodontic file for children's dental treatment, 2020, Patent for Utility Model, ZL201922119495.0
3. Hongmei Zhang, Qiao Liu, Huan Zeng. Assistive devices for identifying dental treatments, 2020, Patent for Utility Model, ZL201922131328.8
