PERSONAL INFORMATION
Name: Enyi Huang
Gender: Female
Title: Doctor
Position: Deputy Director
CONTACT INFORMATION
Email: enyihuang@hospital.cqmu.edu.cn
Address: No. 426 Songshi North Road, Yubei District,
Chongqing, China
Phone: +86-15922677369
EDUCATION EXPERIENCE
2008/09-2012/06, School of Biotechnology, Chongqing University, PhD, Supervisor: Professor Yang Li
2009/10-2011/10，co trained doctoral student, Molecular Oncology Laboratory, Department of Surgery, The University of Chicago Medical Center, Chicago (supported by the National Scholarship Council), Supervisor: Associate Professor Tong-Chuan He
2005/09-2008/06, School of Biotechnology, Chongqing University, Master's degree, Supervisor: Professor Yang Li
2004/11-2009/09, Department of Cell Biology, Army Medical University, Supervisor: Professor Yang Tian
2001/09-2005/06, Bachelor's degree, School of Biotechnology, Chongqing University
WORKING EXPERIENCE
1. 2021/12-present, Associate Professor, School of Stomatology, Chongqing Medical University
2. 2015/3-present, Associate Researcher, School of Stomatology, Chongqing Medical University
3. 2014/07-2021/12, lecturer, School of Stomatology, Chongqing Medical University
4. 2013/02-present, Deputy Director, Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Stomatological Hospital of Chongqing Medical University
5. 2012/11-2015/3, Assistant Researcher, School of Stomatology, Chongqing Medical University
6. 2012/07-present, full-time research personnel, Chongqing Key Laboratory of Oral Diseases and Biomedical Sciences, Stomatological Hospital of Chongqing Medical University
RESEARCH INTERESTS
Research on bone regeneration under pathological conditions; Dental biomechanics
PUBLICATIONS
(1) Mengtian Peng#, Xiaofei Ma#, Yuying Cao, Chunjuan Wang, Qin Tan, Xinyue Chu, Pengfei Zhou, Tiwei Fu, Panpan Liang, Shidian Ran, Tong-Chuan He, Jinhua Wang*, Enyi Huang*, Comparison of the biomechanical differences in the occlusal movement of wild-type and BMP9 knockout mice with apical periodontitis, Frontiers in Bioengineering and Biotechnology, 2022, 10:1036061.
(2) Qin Tan, Yuying Cao, Xiaorong Zheng, Mengtian Peng, Enyi Huang*, Jinhua Wang*, BMP4-regulated human dental pulp stromal cells promote pulp-like tissue regeneration in a decellularized dental pulp matrix scaffold, Odontology, 2021, 109(4):895-903
(3) Tiwei Fu#, Panpan Liang#, Jinlin Song, Jinhua Wang, Pengfei Zhou, Yinhong Tang, Jing Li, Enyi Huang*, Matrigel Scaffolding Enhances BMP9-induced Bone Formation in Dental Follicle Stem/Precursor Cells，International Journal of Medical Sciences，2019, 16(4): 567-575
(4) Yang Song#, Yinhong Tang#, Jinlin Song, Mingxing Lei, Panpan Liang, Tiwei Fu, Xudong Su, Pengfei Zhou, Li Yang, Enyi Huang*, Cyclic mechanical stretch enhances BMP9-induced osteogenic differentiation of mesenchymal stem cells, International Orthopaedics, 2018, 42(4):947-955
(5) Tiwei Fu, Xiangyu Fan, Quanxin Long, Wanyan Deng, Jinlin Song, Enyi Huang*, Comparative analysis of prophages in Streptococcus mutans genomes, Peer J, 2017, 5: e4057
(6) Enyi Huang, Gaohui Zhu, Wei Jiang, Ke Yang, Yanhong Gao, Qing Luo, Jian-Li Gao, Stephanie H Kim, Xing Liu, Mi Li, Qiong Shi, Ning Hu, Linyuan Wang, Hong Liu, Jing Cui, Wenwen Zhang, Ruidong Li, Xiang Chen, Yu-Han Kong, Jiye Zhang, Jinhua Wang, Jikun Shen, Yang Bi, Joseph Statz, Bai-Cheng He, Jinyong Luo, Huicong Wang, Feng Xiong, Hue H. Luu, Rex C. Haydon, Li Yang* and Tong-Chuan He*, Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells, Journal of Bone and Mineral Research, 2012, 27(7):1566-1575
(7) Enyi Huang, Yang Bi, Wei Jiang, Xiaoji Luo, Ke Yang, Jian-Li Gao, Yanhong Gao, Qing Luo, Qiong Shi, Stephanie H Kim, Xing Liu, Mi Li, Ning Hu, Hong Liu, Jing Cui, Wenwen Zhang, Ruidong Li, Xiang Chen, Jikun Shen, Yuhan Kong, Jiye Zhang, Jinhua Wang, Jinyong Luo, Bai-Cheng He, Huicong Wang, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Li Yang*, and Tong-Chuan He*, Conditionally Immortalized Mouse Embryonic Fibroblasts Retain Proliferative Activity without Compromising Multipotent Differentiation Potential, PLoS ONE, 2012, 7(2): e32428
(8) Enyi Huang, Xiaohua Lian, Wei Chen, Tian Yang*, Li Yang*. Characterization of rat hair follicle stem cells selected by vario magnetic activated cell sorting system, Acta histochemica et cytochemica, 2009, 42(5): 129-136
(9) Jing Cui#, Wenwen Zhang#*, Enyi Huang, Jia Wang, Junyi Liao, Ruidong Li, Xinyi Yu, Chen Zhao, Zongyue Zeng, Yi Shu, Ruyi Zhang, Shujuan Yan, Jiayan Lei, Chao Yang, Ke Wu, Ying Wu, Shifeng Huang, Xiaojuan Ji, Alexander Li, Cheng Gong, Chengfu Yuan, Linghuan Zhang, Wei Liu, Bo Huang, Yixiao Feng, Liping An, Bo Zhang, Zhengyu Dai, Yi Shen, Wenping Luo, Xi Wang, Ailong Huang, Hue H. Luu, Russell R. Reid, Jennifer Moriatis Wolf, Gopal Thinakaran, Michael J. Lee, Tong-Chuan He*, BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells, Laboratory Investigation, 2019, 99(1):58-71
(10) Li Xia Gao , Chunxiang Bian, Yan Wu, Muhammad Farrukh Nisar, Shida Chen, Chang Ming Li , Ling Yu, Ping Ji, Enyi Huang, Julia Li Zhong, Label-free electrochemical sensor to investigate the effect of tocopherol on generation of superoxide ions following UV irradiation, J Biol Eng, 2018, 12;12:17
(11) Lin Jiang, Jinlin Song, Xiaolei Hu, Hongmei Zhang, Enyi Huang, Yan Zhang, Feng Deng*, Xiaomian Wu*, The Proteasome Inhibitor Bortezomib Inhibits Inflammatory Response of Periodontal Ligament Cells and Ameliorates Experimental Periodontitis in Rats, Journal of periodontology, 2017, 88(5): 473-483
(12) Yan Wu#, Chunxiang Bian#, Chunlin Zhen, Liu Liu, Zhenghong Lin, Muhammad Farrukh Nisar, Mei Wang, Jörg W. Bartsch, Enyi Huang, Ping Ji, Li Yang, Yanhong Yu, Junfeng Yang, Xuemei Jiang*, Julia Li Zhong*, Telomerase reverse transcriptase mediates EMT through NF-κB signaling in tongue squamous cell carcinoma, Oncotarget, 2017, 8(49): 85492-85503
(13) Li Nie#, Xia Yang#, Liang Duan, Enyi Huang, Zhou Pengfei, Wenping Luo, Yan Zhang, Xingqi Zeng, Ye Qiu, Ting Cai, Conghua Li*, The healing of alveolar bone defects with novel bio-implants composed of Ad-BMP9-transfected rDFCs and CHA scaffolds, Scientific Reports, 2017, 7(1): 6373
(14) Fugui Zhang, Yong Li, Hongmei Zhang, Enyi Huang, Lina Gao, Wenping Luo, Qiang Wei, Jiaming Fan, Dongzhe Song, Junyi Liao, Yulong Zou, Feng Liu, Jianxiang Liu, Jiayi Huang, Dan Guo, Chao Ma, Xue Hu, Li Li, Xiangyang Qu, Liqun Chen, Xinyi Yu, Zhicai Zhang, Tingting Wu, Hue H. Luu, Rex C. Haydon, Jinlin Song, Tong-Chuan He*, and Ping Ji*, Anthelmintic Mebendazole Enhances Cisplatin’s Effect on Suppressing Cell Proliferation and Promotes Differentiation of Head and Neck Squamous Cell Carcinoma (HNSCC), Oncotarget, 2017, 8(8): 12968-12982
(15) Fugui Zhang, Jinglin Song, Hongmei Zhang, Enyi Huang, Dongzhe Song, Viktor Tollemar, Jing Wang, Jinhua Wang, Maryam Mohammed, Qiang Wei, Jiaming Fan, Junyi Liao, Yulong Zou, Feng Liu, Xue Hu, Xiangyang Qu, Liqun Chen, Xinyi Yu, Hue H. Luu, Michael J. Lee, Tong-Chuan He*, and Ping Ji*, Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering, Genes & Diseases, 2016, 3(4): 263-276
(16) Yi Deng, Yuhua Sun, Yanjie Bai, Xiang Gao, Huan Zhang, Anxiu Xu, Enyi Huang, Feng Deng*, Shicheng Wei*, In Vitro Biocompability/Osteogenesis and In Vivo Bone Formation Evalution of Peptide-Decorated Apatite Nanocomposites Assisted via Polydopamine, J Biomed Nanotechnol, 2016, 12(4): 602-618
(17) Jian-Li Gao*, Yan-Mei Shui, Wei Jiang, En-Yi Huang, Qi-Yang Shou, Xin Ji, Bai-Cheng He, Gui-Yuan Lv, Tong-Chuan He*, Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid’s anti-metastatic effect in 4T1 tumor bearing mice, Oncotarget, 2016, 7(44):71802-71816
(18) Hongmei Zhang, Jinhua Wang, Fang Deng, Enyi Huang, Zhengjian Yan, Zhongliang Wang, Youlin Deng, Qian Zhang, Zhonglin Zhang, Jixing Ye, Min Qiao, Ruifang Li, Jing Wang, Qiang Wei, Guolin Zhou, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Feng Deng*, Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs), Biomaterials, 2015, 39: 145-154
(19) Xiang Gao#, Xiaohong Zhang#, Jinlin Song, Xiao Xu, Anxiu Xu, Mengke Wang, Bingwu Xie, Enyi Huang, Feng Deng*, Shicheng Wei*, Osteoinductive peptide-functionalized nanofibers with highly ordered structure as biomimetic scaffolds for bone tissue engineering, Int J Nanomedicine, 2015, 10:7109-7128
(20) Jinhua Wang, Hongmei Zhang, Wenwen Zhang, Enyi Huang, Ning Wang, Ningning Wu, Sheng Wen, Xian Chen, Zhan Liao, Fang Deng, Liangjun Yin, Junhui Zhang, Qian Zhang, Zhengjian Yan, Wei Liu, Zhonglin Zhang, Jixing Ye, Youlin Deng, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Feng Deng*, Bone Morphogenetic Protein-9 Effectively Induces Osteo/Odontoblastic Differentiation of the Reversibly Immortalized Stem Cells of Dental Apical Papilla, Stem Cells and Development, 2014, 23(12):1405-1416
(21) Yanhong Gao*, Enyi Huang, Hongmei Zhang, Jinhua Wang, Ningning Wu, Xian Chen, Ning Wang, Sheng Wen, Guoxin Nan, Fang Deng, Zhan Liao, Di Wu, Bosi Zhang, Junhui Zhang, Rex C. Haydon, Hue H. Luu, Lewis L Shi, and Tong-Chuan He*, Crosstalk between Wnt/β-Catenin and Estrogen Receptor Signaling Synergistically Promotes Osteogenic Differentiation of Mesenchymal Progenitor Cells, PLoS One, 2013 8(12): e82436
(22) Gaurav A. Luther, Joseph Lamplot, Xiang Chen, Richard Rames, Eric R. Wagner, Xing Liu, Akash Paresh, Enyi Huang, Stephanie H. Kim, Jikun Shen, Rex C. Haydon, Tong-Chuan He and Hue H. Luu*, IGFBP5 Domains Exert Distinct Inhibitory Effects on the Tumorigenicity and Metastasis of Human Osteosarcoma, Cancer Letters, 2013, 336(1): 222-230
(23) Ning Hu, Dianming Jiang, Enyi Huang, Xing Liu, Ruidong Li, Xi Liang, Stephanie H Kim, Xiang Chen, Jian-Li Gao, Hongyu Zhang, Wenwen Zhang, Yu-Han Kong, Jiye Zhang, Jinhua Wang, Wei Shui, Xiaoji Luo, Bo Liu, Jing Cui, Mary Rose Rogers, Jikun Shen, Chen Zhao, Ning Wang, Ningning Wu, Hue H. Luu, Rex C. Haydon, Tong-Chuan He* and Wei Huang*, BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal stem cells, Journal of Cell Science, 2013, 126: 532-541
(24) Ke Yang, Jin Chen, Wei Jiang, Enyi Huang, Jing Cui, Stephanie H Kim, Ning Hu, Hong Liu, Wenwen Zhang, Ruidong Li, Xiang Chen, Yuhan Kong, Jiye Zhang, Jinhua Wang, Linyuan Wang, Jikun Shen, Hue H. Luu, Rex C. Haydon, Xiaohua Lian, Tian Yang* and Tong-Chuan He*, Conditional Immortalization Establishes a Repertoire of Mouse Melanocyte Progenitors with Distinct Melanogenic Differentiation Potential, Journal of Investigative Dermatology, 2012, 132(10): 2479-2483
(25) Gaurav Luther, Eric R. Wagner, Gaohui Zhu, Quan Kang, Qing Luo, Joseph Lamplot, Yang Bi, Xiaoji Luo, Jinyong Luo, Chad Teven, Qiong Shi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Ke Yang, Richard Rames, Xing Liu, Mi Li, Ning Hu, Hong Liu, Yuxi Su, Liang Chen, Bai-Cheng He, Guo-Wei Zuo, Zhong-Liang Deng, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He*, BMP-9 Induced Osteogenic Differentiation of Mesenchymal Stem Cells: Molecular Mechanism and Therapeutic Potential, Current Gene Therapy, 2011, 11(3): 229-240
(26) Chad M. Teven, Xing Liu, Ning Hu, Ni Tang, Stephanie H. Kim, Enyi Huang, Ke Yang, Mi Li, Jian-Li Gao, Hong Liu, Ryan B. Natale, Gaurav Luther, Qing Luo, Linyuan Wang, Richard Rames, Yang Bi, Jinyong Luo, Hue H Luu, Rex C Haydon, Russell R Reid and Tong-Chuan He*, Epigenetic Regulation of Mesenchymal Stem Cells: A Focus on Osteogenic and Adipogenic Differentiation, Stem Cells International, 2011:201371
(27) Yuxi Su#, Eric R. Wagner#, Qing Luo, Jiayi Huang, Liang Chen, Bai-Cheng He, Guo-Wei Zuo, Qiong Shi, Bing-Qiang Zhang, Gaohui Zhu, Yang Bi, Jinyong Luo, Xiaoji Luo, Stephanie H. Kim, Jikun Shen, Farbod Rastegar, Enyi Huang, Yanhong Gao, Jian-Li Gao, Ke Yang, Christian Wietholt, Ming Li, Jiaqiang Qin, Rex C. Haydon, Tong-Chuan He, and Hue H. Luu*, Insulin-like Growth Factor Binding Protein 5 Suppresses Tumor Growth and Metastasis of Human Osteosarcoma, Oncogene, 2011, 30(37): 3907-3917
(28) Bai-Cheng He#, Jian-Li Gao#, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Ke Yang, Eric R. Wagner, Linyuan Wang, Ni Tang, Jinyong Luo, Xing Liu, Mi Li, Yang Bi, Jikun Shen, Gaurav Luther, Ning Hu, Qixin Zhou, Hue H. Luu, Rex C. Haydon, Yingming Zhao, and Tong-Chuan He*, Tetrandrine Inhibits Wnt/b-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer, Molecular Pharmacology, 2011, 79(2): 211-219
(29) Eric R. Wagner#, Gaurav Luther#, Gaohui Zhu, Qing Luo, Qiong Shi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Yanhong Gao, Ke Yang, Linyuan Wang, Chad Teven, Xiaoji Luo, Xing Liu, Mi Li, Ning Hu, Yuxi Su, Yang Bi, Bai-Cheng He, Ni Tang, Jinyong Luo, Liang Chen, Guowei Zuo, Richard Rames, Rex C. Haydon, Hue H. Luu*, and Tong-Chuan He*, Defective Osteogenic Differentiation in the Development of Osteosarcoma, Sarcoma, 2011:325238
(30) Eric R. Wagner, Gaohui Zhu, Bing-Qiang Zhang, Qing Luo, Qiong Shi, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Farbod Rastegar, Ke Yang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Yang Bi, Yuxi Su, Jinyong Luo, Xiaoji Luo, Jiayi Huang, Zhong-Liang Deng, Russell R. Reid, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He*, The Therapeutic Potential of the Wnt Signaling Pathway in Bone Metabolic Disorders. Current Molecular Pharmacology, 2011, 4(1): 14-25
(31) Farbod Rastegar, Jian-Li Gao, Deana Shenaq, Qing Luo, Qiong Shi, Stephanie H. Kim, Wei Jiang, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jikun Shen, Ke Yang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Jinyong Luo, Xiaoji Luo, Yang Bi, Xing Liu, Mi Li, Ning Hu, Linyuan Wang, Gaurav Luther, Hue H. Luu, Rex C. Haydon, and Tong-Chuan He*, Lysophosphatidic acid acyltransferase b (LPAATb) promotes tumor growth of human osteosarcoma, PLoS ONE, 2010, 5(12): e14182
(32) Gaurav Luther, Richard Rames, Eric R. Wagner, Gaohui Zhu, Qing Luo, Yang Bi, Stephanie H. Kim, Jian-Li Gao, Enyi Huang, Ke Yang, Linyuan Wang, Xing Liu, Mi Li, Ning Hu, Yuxi Su, Xiaoji Luo, Liang Chen, Jinyong Luo, Rex C. Haydon, Hue H. Luu, Lan Zhou*, and Tong-Chuan He*, Molecular Basis of Differentiation Therapy for Soft Tissue Sarcomas, Trends in Cancer Research, 2010, 6: 69-90
(33) Deana S. Shenaq, Farbod Rastegar, Djuro Petkovic, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Ke Yang, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R. Reid, Hue H. Luu, Rex C. Haydon and Tong-Chuan He*, Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials, Stem Cells International, 2010: 519028
(34) Jinyong Luo, Min Tang, Jiayi Huang, Bai-Cheng He, Jian-Li Gao, Liang Chen, Guo-Wei Zuo, Wenli Zhang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Yang Bi, Xiaoji Luo, Wei Jiang, Yuxi Su, Jikun Shen, Stephanie H. Kim, Enyi Huang, Yanhong Gao, Jian-Zhong Zhou, Ke Yang, Hue H. Luu, Xiaochuan Pan, Rex C. Haydon, Zhong-Liang Deng, and Tong-Chuan He*, TGFb/BMP Type I Receptors ALK1 and ALK2 Are Essential for BMP9-Induced Osteogenic Signaling in Mesenchymal Stem Cells, Journal of Biological Chemistry, 2010, 285(38): 29588-29598
(35) Farbod Rastegar, Deana Shenaq, Jiayi Huang, Wenli Zhang, Bing-Qiang Zhang, Bai-Cheng He, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Eric R. Wagner, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Jian-Zhong Zhou, Yang Bi, Yuxi Su, Gaohui Zhu, Jinyong Luo, Xiaoji Luo, Jiaqiang Qin, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Zhong-Liang Deng, Tong-Chuan He*, Mesenchymal Stem Cells: Molecular characteristics and clinical applications, World Journal of Stem Cells, 2010, 2 (4): 67-80
(36) Wenli Zhang, Zhong-Liang Deng, Liang Chen, Guo-Wei Zuo, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Eric R. Wagner, Farbod Rastegar, Stephanie H. Kim, Wei Jiang, Jikun Shen, Enyi Huang, Yanhong Gao, Jian-Li Gao, Jian-Zhong Zhou, Jinyong Luo, Jiayi Huang, Xiaoji Luo, Yang Bi, Yuxi Su, Ke Yang, Hao Liu, Hue H. Luu, Rex C. Haydon, Tong-Chuan He*, and Bai-Cheng He*, Retinoic Acids Potentiate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells, PLoS ONE, 2010, 5(7): e11917
(37) Liang Chen, Wei Jiang, Jiayi Huang, Bai-Cheng He, Guo-Wei Zuo, Wenli Zhang, Qing Luo, Qiong Shi, Bing-Qiang Zhang, Eric R. Wagner, Jinyong Luo, Min Tang, Christian Wietholt, Xiaoji Luo, Yang Bi, Yuxi Su, Bo Liu, Stephanie H. Kim, Connie J. He, Yawen Hu, Jikun Shen, Farbod Rastegar, Enyi Huang, Yanhong Gao, Jian-Li Gao, Jian-Zhong Zhou, Russell R. Reid, Hue H. Luu, Rex C. Haydon, Tong-Chuan He*, and Zhong-Liang Deng*, Insulin-like Growth Factor 2 (IGF2) Potentiates BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells and Bone Formation, Journal of Bone and Mineral Research, 2010, 25(11): 2447-2459
(38) Youjin Hao, Rafael Montiel, Binghui Li, Enyi Huang, Lewie Zeng, Yongsheng Huang*, Association between androgen receptor gene CAG repeat polymorphism and breast cancer risk: a meta-analysis, Breast Cancer Res Treat, 2010, 124:815-820
(39) Yuanxu Xu, Li Yang, Tian Yang, Mingming Xiang, Enyi Huang, Xiaohua Lian*. Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit during Hair Cycle，Acta Histochem Cytochem，2008，41(6): 157-63
