PERSONAL INFORMATION
Name: Lei Dou
Position: Associate professor/ associate chief physician
Lei Dou, male,
Doctor’s degree, associate chief physician/associate professor, research supervisor.
work in the department of Conservative dentistry and Endodontics, Stomatological Hospital of Chongqing Medical University.
Visiting scholar, Wake forest institute of regenerative medicine,
Member of Chinese Stomatological Association
Young member of the committee of Conservative dentistry and Endodontics, Chinese Stomatological Association
Member of the committee of Gerontology, Chinese Stomatological Association
Member and secretary of the committee of Conservative dentistry and Endodontics, Chongqing Stomatological Association
I am proficient in the treatment of dental pulp diseases, and good at microscopic root canal therapy, tooth bleaching, inlay and onlay restoration, dual-wavelength laser therapy, microscopic endodontic surgery, vital pulp preservation therapy as well as dental pulp revascularization, etc.
The research interest is dental pulp tissue engineering and pulp stem cell biology.
So far, I have hosted 6 scientific research projects and 1 educational reform project. I have published more than 20 scientific articles in international or national academic journal, including 11 SCI papers and 3 CSCD papers as the first author or corresponding author. I was granted 2 national invention patents. I am a reviewer of Cellular and Molecular Life Sciences.
CONTACT INFORMATION
Tel: +86-15922666870
E-mail: 500355@hospital.cqmu.edu.cn
EDUCATION EXPERIENCE
2003 Sep-2008 Jun Bachelor’s Degree Stomatology Sichuan University,
2008 Jul-2010 Jun Master’s Degree Stomatology Sichuan University,
2014 Sep-2017 Dec Doctor’s Degree Clinical Laboratory Science Chongqing medical university
WORKING EXPERIENCE
2010 Jun- present Stomatological Hospital of Chongqing Medical University Department of Conservative dentistry and Endodontics Dentist
RESEARCH INTEREST
Pulp biology, Dental pulp regeneration, Dental stem cell
HONORS & AWARDS
Year 2021 Outstanding communist party member in Stomatological Hospital of Chongqing Medical University
Year 2021 Excellent doctor in Stomatological Hospital of Chongqing Medical University
PUBLICATIONS
Xu X, Li Z, Ai X, Tang Y, Yang D, Dou L. Human three-dimensional dental pulp organoid model for toxicity screening of dental materials on dental pulp cells and tissue. Int Endod J. 2022;55(1):79-88.
Matz EL, Thakker PU, Gu X, Terlecki RP, Dou L, Walker SJ, Lue T, Lin G, Atala A, Yoo JJ, Zhang Y, Jackson JD. Administration of secretome from human placental stem cell-conditioned media improves recovery of erectile function in the pelvic neurovascular injury model. J Tissue Eng Regen Med. 2020;14(10):1394-1402.
Guo H, Deng N, Dou L, Ding H, Criswell T, Atala A, Furdui CM, Zhang Y. 3D Human Renal Tubular Organoids Generated from Urine-Derived Stem Cells for Nephrotoxicity Screening. ACS Biomater Sci Eng 2020;612(12):6701-6709.
Dou L, Yan Q, Yang D. Effect of five dental pulp capping agents on cell proliferation, viability, apoptosis and mineralization of human dental pulp cells. Experimental and Therapeutic Medicine. 2020;19(3): 2377–2383.
Dou L, Matz EL, Gu X, Shu F, Paxton J, Song J, Yoo J, Atala A, Jackson J, Zhang Y. Non-Invasive Cell Tracking with Brighter and Red-Transferred Luciferase for Potential Application in Stem Cell Therapy. Cell Transplant. 2019;28(12):1542-1551.
Jun H, Lei D, Qifang Y, Yuan X, Deqin Y. Effects of concentrated growth factors on the angiogenic properties of dental pulp cells and endothelial cells: an in vitro study. Braz Oral Res. 2018;32:e48.
Dou L, Vanschaayk MM, Zhang Y, Fu X, Ji P, Yang D. The prevalence of dental anxiety and its association with pain and other variables among adult patients with irreversible pulpitis. BMC Oral Health. 2018;18(1):101.
Dou L, Luo J, Fu X, Tang Y, Gao J, Yang D. The validity of caries risk assessment in young adults with past caries experience using a screening Cariogram model without saliva tests. Int Dent J. 2018 68(4):221-226.
Dou L, Yan Q, Liang P, Zhou P, Zhang Y, Ji P. iTRAQ-Based Proteomic Analysis Explore the Influence of Hypoxia on the Proteome of Dental Pulp Stem Cells under 3d Culture. Proteomics. 2018 Feb;18(3-4).
Dou L, Wu Y, Yan Q, Wang J, Zhang Y, Ji P. Secretome profiles of immortalized dental follicle cells using iTRAQ-based proteomic analysis. Sci Rep. 2017;7(1):7300.
Su L, Liu W, Xie B, Dou L, Sun J, Wan W, Fu X, Li G, Huang J, Xu L. Toothbrushing, Blood Glucose and HbA1c: Findings from a Random Survey in Chinese Population. Sci Rep. 2016;6:28824.
Dou L, Li D, Xu T, Tang Y, Yang D. Root anatomy and canal morphology of mandibular first premolars in a Chinese population. Sci Rep. 2017;7(1):750.
Liu J, Luo J, Dou L, Yang D. CBCT study of root and canal morphology of permanent mandibular incisors in a Chinese population. Acta Odontol Scand. 2014;72(1):26-30.
Dou L, Luo J, Yang D. Anaesthetic efficacy of supplemental lingual infiltration of mandibular molars after inferior alveolar nerve block plus buccal infiltration in patients with irreversible pulpitis. Int Endod J. 2013;46(7):660-5.
Dou L, Luo J, Yang D, Wang Y. The effectiveness of an additional lingual infiltration in the pulpal anesthesia of mandibular teeth: a systematic review. Quintessence Int. 2013;44(5):457-64.