PERSONAL INFORMATION
Name: Rui Cheng
Position: Distinguished Associate Professor
Email: rui.cheng@cqmu.edu.cn
Phone: +86-23-68481525
EDUCATION EXPERIENCE
Ph.D. in Biomedical and Pharmaceutic Sciences Catholic University of Louvain, Belgium, 2012
M.S. in Physiology, Cellular and Molecular Biology, University of Poitiers, France, 2006
B.S. in Biochemistry, University of Poitiers, France, 2004
PROFESSIONAL EXPERIENCE
2020-present, Distinguished Associate Professor at ChongQing Medical University
2012-2020, Research Associate Scientist, at Catholic University of Louvain
RESEARCH INTERESTS
Diabetes, Obesity and Mechanisms of hormone secretion
PUBLICATIONS
1. Min Li; Ruifan Zhang; Qian Ge; Lingzhi Yue; Dan Ma; Firas Khattab; Wenhua Xie; Yewei Cui; Patrick Gilon; Xueya Zhao; Xi Li; Rui Cheng; Chemerin as an Inducer of β Cell Proliferation Mediates Mitochondrial Homeostasis and Promotes β Cell Mass Expansion, International Journal of Molecular Sciences, 2023, 24(11), 9136
2. Hong Chen; Qilin Pei; Linfen Tao; Jing Xia; Guocai Lu; Ying Zong; Wenhua Xie; Wanqing Li; Chenglong Huang; Ting Zeng; Xinyu Yu; Weixuan Wang; Gaojun Chen; Song Yang; Rui Cheng*; Xi Li*; ASC Regulates Subcutaneous Adipose Tissue Lipogenesis and Lipolysis via p53/AMPKα Axis, International Journal of Molecular Sciences, 2022, 23(17): 10042-10042
3. Rui Cheng-Xue; Ana Gómez-Ruiz; Nancy Antoine; Laura A. Noël; Hee-Young Chae; Magalie A. Ravier; Fabrice Chimienti; Frans C. Schuit; Patrick Gilon; Tolbutamide Controls Glucagon Release From Mouse Islets Differently Than Glucose. Involvement of KATP Channels From Both a-Cells and d- Cells, Diabetes, 2013, 62(May 2013): 1612-1622
4. Cheng-Xue R, Noel L, Ravier MA, Chimienti F, Schuit FC, Gilon P. Glucose inhibits glucagon secretion from mouse pancreatic islets independently from Zn2+or somatostatin, and from an action on K-ATP channels. Diabetologia. 2010- Vol. 53, no. Suppl. 1, p. S278）
5. Nicolas Quoix#; Rui Cheng-Xue#; Laurine Mattart; Ziad Zeinoun; Yves Guiot; Melanie C. Beauvois; Jean-Claude Henquin; Patrick Gilon; Glucose and Pharmacological Modulators of ATP- Sensitive K Channels Control [Ca2+]c by Different Mechanisms in Isolated Mouse a-Cells, Diabetes, 2009, 58(February): 412-421
6. M. A. Ravier; R. Cheng-Xue; A. E. Palmer; J. C. Henquin; P. Gilon ; Subplasmalemmal Ca2+ measurements in mouse pancreatic beta cells support the existence of an amplifying effect of glucose on insulin secretion, Diabetologia, 2010, 53(2010): 1947-1957
7. Ravier MA, Daro D, Roma LP, Jonas JC, Cheng-Xue R, Schuit F, Gilon P. Mechanisms of control of the free Ca2+ concentration in the endoplasmic reticulum of mouse pancreatic β-cells: interplay with cell metabolism and [Ca2+]c, and role of SERCA2b and SERCA3. Diabetes. 60:2533-2545 (2011)
8. Gilon P, Cheng-Xue R, Gómez-Ruiz A, Antoine N, Noël LA, Chae HY. The control of glucagon secretion by glucose and KATP channel modulators. Proceedings of the Belgian Royal Academies of Medicine 3:129-145 (2014).
9. Quoix N, Cheng-Xue R, Guiot Y, Herrera PL, Henquin JC, Gilon P. The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic α-cells. FEBS Letters. 581:4235–4240 (2007)
10. Gilon P, Cheng-Xue R, Lai BK, Chae HY, Gómez-Ruiz A. Physiological and pathophysiological control of glucagon secretion by pancreatic α-cells. Book chapter in Islam MS (Ed.) “Islets of Langerhans”, 2nd edition, Springer Dordrecht, Heidelberg, New York, London, p175-247 (2015). Written upon invitation by the editor, doi:10.1007/978-94-007-6686-0_37
11. Thorrez L, Laudadio I, Van Deun K, Quintens R, Hendrickx N, Granvik M, Lemaire K, Schraenen A, Van Lommel L, Lehnert S, Aguayo-Mazzucato C, Cheng-Xue R, Gilon P, Van Mechelen I, Bonner-Weir S, Lemaigre F, Schuit F. Tissue-specific disallowance of housekeeping genes: The other face of cell differentiation. Genome Research. 21:95-105 (2011).
