Faculty & Research

Institute of Life Sciences -- MA Shiyong

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PERSONAL INFORMATION

Name: Shiyong (Felix) Ma

Gender: Male

Title: Dr.

Position: Associate Professor

 

CONTACT INFORMATION

Email: shiyongma@cqmu.edu.cn

Address: Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, The Ministry                of Education, Institute of Life Sciences, Chongqing Medical University.

               1# Yixueyuan Road, Yuzhong District, Chongqing 400016, P.R. China.

Phone: +86-13157319086

 

EDUCATION EXPERIENCE

Ph.D in Bioinformatics and Computational Proteomics. Prince of Wales Clinical School, Faculty of Medicine, University of New South Wales, Sydney. 2012-2016.

Supervisors: Dr Jason Wong, Dr Kevin Downard.

Thesis: Computational Methods for Protein Identification and Quantification using Mass Spectrometry.

Master of Engineering in Computer Vision and Machine Learning. The State Key Laboratory of Integrated Services Network (ISN), Communication Engineering College, Xidian University, Xi’an, China, 2009-2012.

Supervisor: Dr Zhaoyang Lu.

http://ste.xidian.edu.cn/english/f-luzhaoyang.html 

Thesis: Research on Three-Dimensional Rectification of Natural Scene Text Images.

Bachelor of Engineering in Electronic and Information Engineering (Information Theory). Communication Engineering College, Xidian University, Xi’an, China, 2005-2009.

 

WORKING EXPERIENCE

Associate Professor, Basic Medicine Research and Innovation Center for Novel Target and Therapeutic Intervention, The Ministry of Education, Institute of Life Sciences,

Chongqing Medical University. 2021.02-Now

Postdoctoral Research Fellow, The Johns Hopkins Medical Institutions. 2017.03 – 2020.12. Supervisor: Dr Zhen Zhang

 

RESEARCH INTERESTS

My current research is at the interface between computer science and system biology. My primary research interest lies in developing statistical and data mining methods for understanding biological data, especially large-scale omics data. The aim is to contribute a better understanding of the human genome in health and disease through the integrative analysis of multi-omics data using new data mining methods.

 

HONOUR & AWARDS

Member of the Computational Biology and Bioinformatics Professional Committee of the China Society of Biotechnology, 2023.5.30-Now

 

PUBLICATIONS

Zhai, Z., Zhang, X., Zhou, L., Lin, Z., Kuang, N., Li, Q., ...Ma, S & Pan, J. (2023). PertOrg 1.0: a comprehensive resource of multilevel alterations induced in model organisms by in vivo genetic perturbation. Nucleic Acids Research, 51(D1), D1094-D1101. IF 19.3

Li, Q*., Ma, S*., Zhang, X., Zhai, Z., Zhou, L., Tao, H., ... & Pan, J. (2022). DDPD 1.0: a manually curated and standardized database of digital properties of approved drugs for drug-likeness evaluation and drug development. Database. IF 3.451

Song Jin*, Ma S*, Sokoll L, Eguez R, Höti N, Zhang H, … , Chan D.W, Zhang Z. (2021) A panel of selected serum protein biomarkers for the detection of aggressive prostate cancer. Theranostics,11(13),6214. IF 11.556

Clark, D. J., Dhanasekaran, S. M., Petralia, F., Pan, J., Song, X., Hu, Y., ... , Ma S, ... & Zhang Hui. (2019). Integrated proteogenomic characterization of clear cell renal cell carcinoma. Cell, 179(4), 964-983. IF 38.637

Ma S, Downard KM, Wong JWH (2017) Phylogenetic Analysis using Protein Mass Spectrometry, in Methods in Molecular Biology: Proteome Bioinformatics (eds. Mathivanan S, Keerthikumar S), Springer, Berlin.

Ma S, Menon R, Poulos RC, Wong JWH (2017) Proteogenomic analysis prioritises functional single nucleotide variants in cancer samples. Oncotarget. IF 3.710

Unnikrishnan A#*, Guan Y#, Huang Y, Beck D, … , Ma S, … , Wong JWH and Pimanda J.E* (2016). A quantitative proteomics approach identifies new regulators of an ERG-driven transcriptional network. Nucleic Acids Research. IF 11.501

Ma S, Downard KM, Wong JWH. (2015). FluClass: A novel algorithm and approach to score and visualize the phylogeny of the influenza virus using mass spectrometry. Analytica Chimica Acta. IF 5.977