PERSONAL INFORMATION
Name: Zhou Changlong
Gender: Male
Title: M.D
CONTACT INFORMATION
Email: cqzhoulong@aliyun.com
Address: 439 Xuanhua Road, Yongchuan District, Chongqing,
People's Republic of China
Phone: +86-13996002062
EDUCATION EXPERIENCE
B.S. Clinical Medicine, Southwest Medical University, P. R. China Sept 1996-June 2001
M.Sc. Neurosurgery, Chongqing Medical University, P. R. China Sept 2010-June 2013
M.D Neurosurgery, Chongqing Medical University, P. R. China Sept 2015-June 2019
WORKING EXPERIENCE
2001.7-2008.7 Resident, Department of neurosurgery, Yongchuan Hospital of Chongqing Medical University
2008.7-2013.4 Attending physician, Department of neurosurgery,Yongchuan Hospital of Chongqing Medical University
2013.4-2020.4 Associate Senior physician, Department of neurosurgery,Yongchuan Hospital of Chongqing Medical University
2020.4-Present Chief Physician, Department of neurosurgery,Yongchuan Hospital of Chongqing Medical University
RESEARCH INTERESTS
The main research interest of Dr. Zhou is To investigate the effect of estrogen on axon regeneration and neurological recovery after subcortical axon injury,and further explore its underlying molecular mechanisms. Subcortical axonal fiber injury model was used in this study.Morris water maze was conducted to detect the learning and memory ability of the rats; modified neurological severity score (mNSS) and beam walking test were performed to evaluate the behavioral; and diffusion tensor imaging (DTI) was used for the determination of recovery aftersubcortical axonal injury,while Western blotting was performed to detect the expression of p-Akt, CDK5, p-Ser262,p-Ser404,and p-Thr205.The study revealed that after subcortical axonal injury, estrogen could improve the regeneration of axons and improve their functions via regulating the PI3K/Akt/CDK5/Tau pathway. The relevant outputs were published in the Brain and Behavior.
PUBLICATIONS
1. Changlong Zhou Xiaohui Xia Xiaochuan Sun etc. Estrogen improved the regeneration of axons after subcortical axon injury via regulation of PI3K/Akt/CDK5/Tau pathway. Brain and Behavior, 2020.10(9)
2. Changlong Zhou, Qingjun Liu, Wang Zhao etc. Nrdp1 increases neuron apoptosis via downregulation of Bruce following intracerebral haemorrhage. Journal of Inflammation 2019.1
